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- W2110368747 abstract "To determine if remifentanil would offer a superior hemodynamic and recovery profile compared to the current standard of care, which implements a fentanyl-based technique.Randomized, single-blind study.Outpatient center associated with tertiary care center.75 outpatients undergoing microsuspension laryngoscopy.Patients were randomized to either a remifentanil induction (0.5 microg/kg/min) and maintenance (0.25 microg/kg/min) versus fentanyl (maximum of 250 microg) as the only opioid. All patients received propofol as part of the induction and maintenance with or without the use of nitrous oxide.Assessment of hemodynamics [heart rate (HR) and blood pressure(BP)], presence of perioperative myocardial ischemia on ambulatory electrocardiographic monitoring, and time to discharge.Significantly fewer patients in the remifentanil group demonstrated episodes of tachycardia (HR > 100 beats per min) compared to the fentanyl group (14% vs. 40%, p<0.05), with significantly fewer episodes of tachycardia and hypertension per patient. Recovery profiles between the two groups did not show clinically significant differences.Remifentanil, a new short-acting opioid, offers excellent hemodynamic control for brief, intense outpatient procedures performed in high-risk patients; however, its use was not associated with any improvement in recovery profiles." @default.
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- W2110368747 date "2000-09-01" @default.
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- W2110368747 title "Effectiveness of Remifentanil versus traditional fentanyl-based anesthetic in high-risk outpatient surgery" @default.
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- W2110368747 doi "https://doi.org/10.1016/s0952-8180(00)00185-9" @default.
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