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- W2110393428 abstract "Background: Restless-legs syndrome (RLS) is known to be caused by dopaminergic hypofunction in the brain. We investigated whether antipsychotics that act as antidopaminergics increase the risk of RLS. Methods: We prospectively recruited 72 schizophrenic patients who had been medicated with antipsychotic drugs in a psychiatry clinic. We evaluated RLS diagnostic criteria and basic sleep habits using the Epworth Sleepiness Scale and Pittsburgh Sleep Quality Index by face-to-face interviews using a structured questionnaire. We also applied the Unified Parkinson’s Disease Rating Scale to evaluate extrapyramidal symptoms. Results: Three of the 72 patients (4.2%) met RLS criteria, which is similar to the previously reported RLS incidence among the general population in Korea. Conclusions: There is no evidence that antipsychotics increase the risk of RLS. We believe that the mild antidopaminergic effect of antipsychotics does not overwhelm their prominent antipsychotic effect. J Korean Neurol Assoc 27(1):49-53, 2009" @default.
- W2110393428 created "2016-06-24" @default.
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- W2110393428 date "2009-01-01" @default.
- W2110393428 modified "2023-09-26" @default.
- W2110393428 title "Is Antipsychotic Intake a Risk Factor for the Restless Legs Syndrome" @default.
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