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- W2110396961 endingPage "705" @default.
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- W2110396961 abstract "The incidence of infectious diseases, particularly respiratory diseases, increases with age. Age-associated decline in immune function contributes to the increased susceptibility of the aged to infections. Vitamin E supplementation has been shown to improve some aspects of immune function in aged animals and human subjects. The protective effect of vitamin E against viral or bacterial infections in experimentally-challenged young animals has been reported. We investigated the effects of supplementation with vitamin E and other antioxidants on resistance to influenza infection in young and old animals. While vitamin E-supplemented young mice showed only a modest reduction in lung viral titre, vitamin E-supplemented old mice exhibited a highly significant (P < 0.05) reduction in viral lung titre. In subsequent studies, we focused on the mechanism of vitamin E-induced reduction of influenza viral titre. The results of these studies as well as those reported by other investigators on the relationship between vitamin E and infectious diseases will be reviewed." @default.
- W2110396961 created "2016-06-24" @default.
- W2110396961 creator A5030986047 @default.
- W2110396961 creator A5064829479 @default.
- W2110396961 date "1999-08-01" @default.
- W2110396961 modified "2023-10-12" @default.
- W2110396961 title "Vitamin E and infectious diseases in the aged" @default.
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- W2110396961 doi "https://doi.org/10.1017/s0029665199000919" @default.
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