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- W2110403750 abstract "Abstract A general procedure for the preparation of C 3 ‐symmetric TREN derivatives with backbone chirality has been developed. Stereo‐ and regioselective ring opening by ammonia of ( S )‐ N ‐tosyl‐2‐isopropylaziridine, obtained starting from either the corresponding amino alcohol or amino acid, followed by deprotection of the amino groups afforded the parent chiral TREN compound in high overall yield. In addition to TREN compounds with primary amino groups, the synthetic method employed provides easy access to a variety of N , N' , N'' ‐substituted derivatives. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)" @default.
- W2110403750 created "2016-06-24" @default.
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- W2110403750 date "2005-06-20" @default.
- W2110403750 modified "2023-10-14" @default.
- W2110403750 title "A General Method for the Preparation of Chiral TREN Derivatives" @default.
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- W2110403750 doi "https://doi.org/10.1002/ejoc.200500094" @default.
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