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• W2110409905 endingPage "102601" @default.
• W2110409905 startingPage "102601" @default.
• W2110409905 abstract "Research opportunities and techniques are reviewed for the application of hard x-ray pulsed free-electron lasers (XFEL) to structural biology. These include the imaging of protein nanocrystals, single particles such as viruses, pump--probe experiments for time-resolved nanocrystallography, and snapshot wide-angle x-ray scattering (WAXS) from molecules in solution. The use of femtosecond exposure times, rather than freezing of samples, as a means of minimizing radiation damage is shown to open up new opportunities for the molecular imaging of biochemical reactions at room temperature in solution. This is possible using a 'diffract-and-destroy' mode in which the incident pulse terminates before radiation damage begins. Methods for delivering hundreds of hydrated bioparticles per second (in random orientations) to a pulsed x-ray beam are described. New data analysis approaches are outlined for the correlated fluctuations in fast WAXS, for protein nanocrystals just a few molecules on a side, and for the continuous x-ray scattering from a single virus. Methods for determining the orientation of a molecule from its diffraction pattern are reviewed. Methods for the preparation of protein nanocrystals are also reviewed. New opportunities for solving the phase problem for XFEL data are outlined. A summary of the latest results is given, which now extend to atomic resolution for nanocrystals. Possibilities for time-resolved chemistry using fast WAXS (solution scattering) from mixtures is reviewed, toward the general goal of making molecular movies of biochemical processes." @default.
• W2110409905 created "2016-06-24" @default.
• W2110409905 creator A5048625174 @default.
• W2110409905 creator A5050336210 @default.
• W2110409905 creator A5077780833 @default.
• W2110409905 date "2012-09-13" @default.
• W2110409905 modified "2023-10-16" @default.
• W2110409905 title "X-ray lasers for structural and dynamic biology" @default.
• W2110409905 cites W1492556495 @default.
• W2110409905 cites W1625860372 @default.
• W2110409905 cites W1847564501 @default.
• W2110409905 cites W1963491088 @default.
• W2110409905 cites W1966265504 @default.
• W2110409905 cites W1966955841 @default.
• W2110409905 cites W1968901187 @default.
• W2110409905 cites W1971773700 @default.
• W2110409905 cites W1973881708 @default.
• W2110409905 cites W1975599026 @default.
• W2110409905 cites W1976684703 @default.
• W2110409905 cites W1978971439 @default.
• W2110409905 cites W1979335921 @default.
• W2110409905 cites W1979379233 @default.
• W2110409905 cites W1980446562 @default.
• W2110409905 cites W1981679042 @default.
• W2110409905 cites W1984370357 @default.
• W2110409905 cites W1986605659 @default.
• W2110409905 cites W1987142543 @default.
• W2110409905 cites W1987587134 @default.
• W2110409905 cites W1988662633 @default.
• W2110409905 cites W1992326972 @default.
• W2110409905 cites W1998019040 @default.
• W2110409905 cites W1998196350 @default.
• W2110409905 cites W2000022645 @default.
• W2110409905 cites W2001265759 @default.
• W2110409905 cites W2002849329 @default.
• W2110409905 cites W2003959143 @default.
• W2110409905 cites W2004568553 @default.
• W2110409905 cites W2007593159 @default.
• W2110409905 cites W2008741619 @default.
• W2110409905 cites W2009004457 @default.
• W2110409905 cites W2009151212 @default.
• W2110409905 cites W2010233094 @default.
• W2110409905 cites W2010542152 @default.
• W2110409905 cites W2011592317 @default.
• W2110409905 cites W2012919336 @default.
• W2110409905 cites W2013427992 @default.
• W2110409905 cites W2014626876 @default.
• W2110409905 cites W2017546790 @default.
• W2110409905 cites W2020601776 @default.
• W2110409905 cites W2021255186 @default.
• W2110409905 cites W2022522071 @default.
• W2110409905 cites W2022632140 @default.
• W2110409905 cites W2023823387 @default.
• W2110409905 cites W2024094194 @default.
• W2110409905 cites W2027427189 @default.
• W2110409905 cites W2033172393 @default.
• W2110409905 cites W2033796939 @default.
• W2110409905 cites W2036591011 @default.
• W2110409905 cites W2038279917 @default.
• W2110409905 cites W2041546300 @default.
• W2110409905 cites W2044613770 @default.
• W2110409905 cites W2044862293 @default.
• W2110409905 cites W2047087020 @default.
• W2110409905 cites W2047189595 @default.
• W2110409905 cites W2050444770 @default.
• W2110409905 cites W2051560278 @default.
• W2110409905 cites W2052377979 @default.
• W2110409905 cites W2055789341 @default.
• W2110409905 cites W2057398812 @default.
• W2110409905 cites W2058375309 @default.
• W2110409905 cites W2058657473 @default.
• W2110409905 cites W2058837354 @default.
• W2110409905 cites W2059090037 @default.
• W2110409905 cites W2063123200 @default.
• W2110409905 cites W2066593550 @default.
• W2110409905 cites W2069723609 @default.
• W2110409905 cites W2072558823 @default.
• W2110409905 cites W2073620060 @default.
• W2110409905 cites W2074998400 @default.
• W2110409905 cites W2076575551 @default.
• W2110409905 cites W2076596341 @default.
• W2110409905 cites W2079460143 @default.
• W2110409905 cites W2079866647 @default.
• W2110409905 cites W2084069427 @default.
• W2110409905 cites W2084653011 @default.
• W2110409905 cites W2086859049 @default.
• W2110409905 cites W2087432921 @default.
• W2110409905 cites W2088549765 @default.
• W2110409905 cites W2091826247 @default.
• W2110409905 cites W2092832311 @default.
• W2110409905 cites W2093638263 @default.
• W2110409905 cites W2093652605 @default.
• W2110409905 cites W2096022565 @default.
• W2110409905 cites W2098451382 @default.
• W2110409905 cites W2107242593 @default.
• W2110409905 cites W2108914136 @default.
• W2110409905 cites W2109021861 @default.
• W2110409905 cites W2110893691 @default.

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