FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110442885> ?p ?o ?g. }

• W2110442885 endingPage "418" @default.
• W2110442885 startingPage "413" @default.
• W2110442885 abstract "We searched for genes with expressions specific to human monocyte-derived dendritic cells (DCs) using differential display reverse transcription-polymerase chain reaction, and found that N-myc downstream regulated gene 2 (NDRG2), a member of a new family of differentiation-related genes, was expressed in DCs. While DCs derived from CD34(+) progenitor cells also showed strong NDRG2 expression, the corresponding mRNA expression was absent in other cell lines including monocytes, B cells, and NK cells. The inhibition of DC differentiation by dexamethasone or vitamin D(3) treatment down-regulated the expression of the NDRG2 gene in DCs. In addition, gene expression was induced in a myelomonocytic leukemia cell line, which is capable of differentiating into DCs in cytokine-conditioned culture. The level of NDRG2 gene expression in DCs was significantly higher than that of other members of the NDRG gene family. Finally, in contrast to the stable NDRG2 expression in CD40-stimulated DCs, the induction of DC maturation by lipopolysaccharide (LPS) resulted in the down-regulation of NDRG2 gene expression. This down-regulation is likely to be due to a modification and subsequent destabilization of NDRG2 mRNA, because co-treating with actinomycin D and LPS significantly blocked this LPS effect. Taken together, our results indicate that NDRG2 is expressed during the differentiation of DCs, and that NDRG2 gene expression is differentially regulated by maturation-inducing stimuli." @default.
• W2110442885 created "2016-06-24" @default.
• W2110442885 creator A5008316550 @default.
• W2110442885 creator A5015889041 @default.
• W2110442885 creator A5039448459 @default.
• W2110442885 creator A5063022953 @default.
• W2110442885 creator A5072195745 @default.
• W2110442885 creator A5076397278 @default.
• W2110442885 creator A5077530265 @default.
• W2110442885 creator A5087456386 @default.
• W2110442885 creator A5088816534 @default.
• W2110442885 date "2003-10-03" @default.
• W2110442885 modified "2023-09-26" @default.
• W2110442885 title "Expression and regulation of NDRG2 (N-myc downstream regulated gene 2) during the differentiation of dendritic cells" @default.
• W2110442885 cites W1020248866 @default.
• W2110442885 cites W144824218 @default.
• W2110442885 cites W1499902555 @default.
• W2110442885 cites W1502937057 @default.
• W2110442885 cites W1561535731 @default.
• W2110442885 cites W1566527570 @default.
• W2110442885 cites W1579102917 @default.
• W2110442885 cites W1604635829 @default.
• W2110442885 cites W1649547160 @default.
• W2110442885 cites W1955379330 @default.
• W2110442885 cites W1965785232 @default.
• W2110442885 cites W1966052560 @default.
• W2110442885 cites W1979179301 @default.
• W2110442885 cites W1981743414 @default.
• W2110442885 cites W1989479343 @default.
• W2110442885 cites W1995530329 @default.
• W2110442885 cites W2002449179 @default.
• W2110442885 cites W2009943989 @default.
• W2110442885 cites W2046887163 @default.
• W2110442885 cites W2048925802 @default.
• W2110442885 cites W2050837935 @default.
• W2110442885 cites W2058475298 @default.
• W2110442885 cites W2063100299 @default.
• W2110442885 cites W2064346335 @default.
• W2110442885 cites W2065661920 @default.
• W2110442885 cites W2067131315 @default.
• W2110442885 cites W2080097192 @default.
• W2110442885 cites W2082521416 @default.
• W2110442885 cites W2100200230 @default.
• W2110442885 cites W2110296049 @default.
• W2110442885 cites W2111220263 @default.
• W2110442885 cites W2111360453 @default.
• W2110442885 cites W2119984866 @default.
• W2110442885 cites W2131761283 @default.
• W2110442885 cites W2137577449 @default.
• W2110442885 cites W2142101377 @default.
• W2110442885 cites W2156498845 @default.
• W2110442885 cites W2156863356 @default.
• W2110442885 cites W4233851404 @default.
• W2110442885 cites W4313331452 @default.
• W2110442885 cites W4313347910 @default.
• W2110442885 cites W90568390 @default.
• W2110442885 doi "https://doi.org/10.1016/s0014-5793(03)01030-5" @default.
• W2110442885 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14572661" @default.
• W2110442885 hasPublicationYear "2003" @default.
• W2110442885 type Work @default.
• W2110442885 sameAs 2110442885 @default.
• W2110442885 citedByCount "88" @default.
• W2110442885 countsByYear W21104428852012 @default.
• W2110442885 countsByYear W21104428852013 @default.
• W2110442885 countsByYear W21104428852014 @default.
• W2110442885 countsByYear W21104428852015 @default.
• W2110442885 countsByYear W21104428852016 @default.
• W2110442885 countsByYear W21104428852017 @default.
• W2110442885 countsByYear W21104428852018 @default.
• W2110442885 countsByYear W21104428852019 @default.
• W2110442885 countsByYear W21104428852020 @default.
• W2110442885 countsByYear W21104428852021 @default.
• W2110442885 countsByYear W21104428852023 @default.
• W2110442885 crossrefType "journal-article" @default.
• W2110442885 hasAuthorship W2110442885A5008316550 @default.
• W2110442885 hasAuthorship W2110442885A5015889041 @default.
• W2110442885 hasAuthorship W2110442885A5039448459 @default.
• W2110442885 hasAuthorship W2110442885A5063022953 @default.
• W2110442885 hasAuthorship W2110442885A5072195745 @default.
• W2110442885 hasAuthorship W2110442885A5076397278 @default.
• W2110442885 hasAuthorship W2110442885A5077530265 @default.
• W2110442885 hasAuthorship W2110442885A5087456386 @default.
• W2110442885 hasAuthorship W2110442885A5088816534 @default.
• W2110442885 hasBestOaLocation W21104428851 @default.
• W2110442885 hasConcept C104317684 @default.
• W2110442885 hasConcept C148738053 @default.
• W2110442885 hasConcept C150194340 @default.
• W2110442885 hasConcept C153911025 @default.
• W2110442885 hasConcept C165864922 @default.
• W2110442885 hasConcept C185592680 @default.
• W2110442885 hasConcept C54355233 @default.
• W2110442885 hasConcept C81885089 @default.
• W2110442885 hasConcept C86803240 @default.
• W2110442885 hasConcept C95444343 @default.
• W2110442885 hasConceptScore W2110442885C104317684 @default.
• W2110442885 hasConceptScore W2110442885C148738053 @default.
• W2110442885 hasConceptScore W2110442885C150194340 @default.
• W2110442885 hasConceptScore W2110442885C153911025 @default.

• next