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- W2110451314 abstract "Lipidomics is a new term to describe a scientific field that is a lot broader than lipidology, the science of lipids. Besides lipidology, lipidomics covers the lipid‐metabolizing enzymes and lipid transporters, their genes and regulation; the quantitative determination of lipids in space and time, and the study of lipid function. Because lipidomics is concerned with all lipids and their enzymes and genes, it faces the formidable challenge to develop enabling technologies to comprehensively measure the expression, location, and regulation of lipids, enzymes, and genes in time, including high‐throughput applications. The second challenge is to devise information technology that allows the construction of metabolic maps by browsing through connected databases containing the subsets of data in lipid structure, lipid metabolomics, proteomics, and genomics. In addition, to understand lipid function, on the one hand we need a broad range of imaging techniques to define where exactly the relevant events happen in the body, cells, and subcellular organelles; on the other hand, we need a thorough understanding of how lipids physically interact, especially with proteins. The final challenge is to apply this knowledge in the diagnosis, monitoring, and cure of lipid‐related diseases." @default.
- W2110451314 created "2016-06-24" @default.
- W2110451314 creator A5012503437 @default.
- W2110451314 creator A5030256996 @default.
- W2110451314 creator A5042625397 @default.
- W2110451314 creator A5056505416 @default.
- W2110451314 creator A5070833222 @default.
- W2110451314 date "2007-01-01" @default.
- W2110451314 modified "2023-10-17" @default.
- W2110451314 title "The European Lipidomics Initiative: Enabling Technologies" @default.
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- W2110451314 doi "https://doi.org/10.1016/s0076-6879(07)32009-0" @default.
- W2110451314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17954219" @default.
- W2110451314 hasPublicationYear "2007" @default.