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• W2110484499 abstract "The J-F intercistronic region of bacteriophage G4 has the potential to form a perfectly base-paired hairpin structure, thought to act as a terminator of transcription. To investigate this proposed structure-function relationship, viable mutants were constructed by site-specific mutagenesis with small deletions of 2 to 4 base pairs in the center of the corresponding palindromic sequence. These sequence modifications had a small positive effect on the growth efficiency of the phage. The approach of biochemical rather than biological selection of these mutant phages is generally applicable to the construction of virus and plasmid vectors." @default.
• W2110484499 created "2016-06-24" @default.
• W2110484499 creator A5010798008 @default.
• W2110484499 date "1983-10-01" @default.
• W2110484499 modified "2023-09-25" @default.
• W2110484499 title "Enzymatic construction and selection of bacteriophage G4 mutants with modifications of a DNA secondary structure in the J-F intercistronic region" @default.
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• W2110484499 doi "https://doi.org/10.1128/jvi.48.1.170-179.1983" @default.
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