FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110492784> ?p ?o ?g. }

• W2110492784 endingPage "720" @default.
• W2110492784 startingPage "713" @default.
• W2110492784 abstract "No authors have investigated whether the administration of local oestrogens in addition to antimuscarinics could have a synergistic effect in the therapy of overactive bladder (OAB). To compare the efficacy of antimuscarinics alone versus antimuscarinics in combination with local oestrogens for OAB; to verify whether risk factors for lower antimuscarinic efficacy can be overcome by the concomitant use of local oestrogens. Some 229 postmenopausal women with symptomatic urodynamically proven detrusor overactivity were prospectively enrolled at a tertiary level urogynaecology centre and divided into two groups. Women in group 1 (n = 129) were prescribed tolterodine extended release (ER) 4 mg once daily; women in group 2 (n = 100) were prescribed both tolterodine ER 4 mg and concomitant oestriol cream application once daily. All women underwent clinical evaluation and urodynamics in accordance with the Good Urodynamic Practices Guidelines. After 12 wk of treatment the two groups were compared in terms of subjective efficacy for OAB symptom improvement using a three-point scale. Nonresponders were compared to the patients who improved or were cured in order to identify risk factors for resistance to therapy. There was no significant difference between the two groups in terms of efficacy of therapy: 80.6% in group 1 versus 82% in group 2 (p = 0.86). Patients with urodynamically proven detrusor overactivity (DO) occurring during provocative manoeuvres and patients with coital incontinence during orgasm reported a higher failure rate both in the overall study population and in group 2. A possible limitation of the study is the nonrandomised design. No synergistic effect of local oestrogens and antimuscarinics in the treatment of OAB was found. Antimuscarinic treatment has lower cure rates in women with symptomatic DO complaining of incontinence at orgasm or in patients with DO following provocative manoeuvres. The association of local oestrogens does not influence the role of the two mentioned risk factors." @default.
• W2110492784 created "2016-06-24" @default.
• W2110492784 creator A5009441165 @default.
• W2110492784 creator A5011886416 @default.
• W2110492784 creator A5031776828 @default.
• W2110492784 creator A5063830550 @default.
• W2110492784 creator A5081165728 @default.
• W2110492784 date "2009-03-01" @default.
• W2110492784 modified "2023-09-26" @default.
• W2110492784 title "Is There a Synergistic Effect of Topical Oestrogens When Administered with Antimuscarinics in the Treatment of Symptomatic Detrusor Overactivity?" @default.
• W2110492784 cites W1568619399 @default.
• W2110492784 cites W1912852629 @default.
• W2110492784 cites W1967347194 @default.
• W2110492784 cites W1968860914 @default.
• W2110492784 cites W1971566600 @default.
• W2110492784 cites W1993268221 @default.
• W2110492784 cites W1996107218 @default.
• W2110492784 cites W2002152924 @default.
• W2110492784 cites W2005826390 @default.
• W2110492784 cites W2009384973 @default.
• W2110492784 cites W2021632936 @default.
• W2110492784 cites W2022110304 @default.
• W2110492784 cites W2026599479 @default.
• W2110492784 cites W2027843012 @default.
• W2110492784 cites W2032650666 @default.
• W2110492784 cites W2034265241 @default.
• W2110492784 cites W2043533523 @default.
• W2110492784 cites W2043741812 @default.
• W2110492784 cites W2048946213 @default.
• W2110492784 cites W2087817034 @default.
• W2110492784 cites W2089635159 @default.
• W2110492784 cites W2091659519 @default.
• W2110492784 cites W2097625183 @default.
• W2110492784 cites W2109846612 @default.
• W2110492784 cites W2114213251 @default.
• W2110492784 cites W2126110442 @default.
• W2110492784 cites W2134817985 @default.
• W2110492784 cites W2136548062 @default.
• W2110492784 cites W2140643650 @default.
• W2110492784 cites W2141584852 @default.
• W2110492784 cites W2149824548 @default.
• W2110492784 cites W2166571150 @default.
• W2110492784 doi "https://doi.org/10.1016/j.eururo.2008.06.051" @default.
• W2110492784 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18584946" @default.
• W2110492784 hasPublicationYear "2009" @default.
• W2110492784 type Work @default.
• W2110492784 sameAs 2110492784 @default.
• W2110492784 citedByCount "47" @default.
• W2110492784 countsByYear W21104927842012 @default.
• W2110492784 countsByYear W21104927842013 @default.
• W2110492784 countsByYear W21104927842014 @default.
• W2110492784 countsByYear W21104927842015 @default.
• W2110492784 countsByYear W21104927842016 @default.
• W2110492784 countsByYear W21104927842017 @default.
• W2110492784 countsByYear W21104927842018 @default.
• W2110492784 countsByYear W21104927842019 @default.
• W2110492784 countsByYear W21104927842020 @default.
• W2110492784 countsByYear W21104927842021 @default.
• W2110492784 countsByYear W21104927842022 @default.
• W2110492784 countsByYear W21104927842023 @default.
• W2110492784 crossrefType "journal-article" @default.
• W2110492784 hasAuthorship W2110492784A5009441165 @default.
• W2110492784 hasAuthorship W2110492784A5011886416 @default.
• W2110492784 hasAuthorship W2110492784A5031776828 @default.
• W2110492784 hasAuthorship W2110492784A5063830550 @default.
• W2110492784 hasAuthorship W2110492784A5081165728 @default.
• W2110492784 hasConcept C126322002 @default.
• W2110492784 hasConcept C126894567 @default.
• W2110492784 hasConcept C142724271 @default.
• W2110492784 hasConcept C204787440 @default.
• W2110492784 hasConcept C2777844464 @default.
• W2110492784 hasConcept C2778689640 @default.
• W2110492784 hasConcept C2778941218 @default.
• W2110492784 hasConcept C2779384505 @default.
• W2110492784 hasConcept C2781020410 @default.
• W2110492784 hasConcept C2908647359 @default.
• W2110492784 hasConcept C71924100 @default.
• W2110492784 hasConcept C99454951 @default.
• W2110492784 hasConceptScore W2110492784C126322002 @default.
• W2110492784 hasConceptScore W2110492784C126894567 @default.
• W2110492784 hasConceptScore W2110492784C142724271 @default.
• W2110492784 hasConceptScore W2110492784C204787440 @default.
• W2110492784 hasConceptScore W2110492784C2777844464 @default.
• W2110492784 hasConceptScore W2110492784C2778689640 @default.
• W2110492784 hasConceptScore W2110492784C2778941218 @default.
• W2110492784 hasConceptScore W2110492784C2779384505 @default.
• W2110492784 hasConceptScore W2110492784C2781020410 @default.
• W2110492784 hasConceptScore W2110492784C2908647359 @default.
• W2110492784 hasConceptScore W2110492784C71924100 @default.
• W2110492784 hasConceptScore W2110492784C99454951 @default.
• W2110492784 hasIssue "3" @default.
• W2110492784 hasLocation W21104927841 @default.
• W2110492784 hasLocation W21104927842 @default.
• W2110492784 hasOpenAccess W2110492784 @default.
• W2110492784 hasPrimaryLocation W21104927841 @default.
• W2110492784 hasRelatedWork W1507298952 @default.
• W2110492784 hasRelatedWork W1542102176 @default.
• W2110492784 hasRelatedWork W159756094 @default.

• next