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- W2110551480 abstract "This report analyses dose-time-volume factors in 112 patients with T3N0M0 glottic cancer who were treated with radical radiotherapy with surgery for salvage.between 1%3 and 1977. 55 % of the patients are alive and well 5 years following treatment; 26 % died of glottic cancer and 19 % died of intercurrent disease. In the 1965–1969, time period 31 % died of tumor as compared to 16% in the 1975–1977 time period. Overall local control by radiotherapy was 51 %;of the failures were surgically salvaged. 44% were locally controlled by radiotherapy in the 1965–1969 time period and 57% in the 1975–1977 time period. Analysis of dose-time-volume factors reveals that the optimal dose is greater than 1700 ret and a minimal volume of 6 x 8 cm. should be used. A dose-cure curve for T3 glottic cancer is constructed and compared with the dose complication curve for the larynx and the dose-cure curve for TIN0M0 glottic cancer. A comparison of cure rates between 112 patients treated with radical radiotherapy and surgery for salvage versus 28 patients treated with combined pre-operative irradiation and surgery reveals no difference in the proportion of patients who died of glottic cancer or in the number of patients alive at 5 years following treatment." @default.
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- W2110551480 date "1980-06-01" @default.
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- W2110551480 title "T3 glottic cancer: An analysis of dose time-volume factors" @default.
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- W2110551480 doi "https://doi.org/10.1016/0360-3016(80)90222-9" @default.
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