Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110588388> ?p ?o ?g. }
- W2110588388 endingPage "295" @default.
- W2110588388 startingPage "281" @default.
- W2110588388 abstract "Clevidipine butyrate is an ultrashort-acting intravenous dihydropyridine calcium-channel blocker that has been approved by the FDA for the reduction of blood pressure when oral therapy is not feasible. Hypertension is a global disease that affects more than 1 billion people worldwide and 75 million people in the USA. There are multiple agents available for the management of hypertension. The acute setting is where the challenge arises for developing new agents that not only decrease, but more importantly, optimally control blood pressure. Many drugs lower blood pressure; however, only a few have the capacity to precisely control hypertension in the acute phase. Clevidipine has unique pharmacodynamic and pharmacokinetic properties that enable the fast, safe and adequate reduction of blood pressure in hypertensive emergencies, with unique precision necessary to maintain the target blood pressure range. Its use in different clinical settings has been evaluated in several Phase I, II and III clinical studies. It is easily administered and titrated with minimal side effects, achieves fast control with low doses, is highly successful as monotherapy and allows excellent transition to oral medication. Thus, clevidipine is a promising new agent for the management of acute hypertension in a variety of clinical settings." @default.
- W2110588388 created "2016-06-24" @default.
- W2110588388 creator A5015812178 @default.
- W2110588388 creator A5039382366 @default.
- W2110588388 date "2010-01-21" @default.
- W2110588388 modified "2023-09-24" @default.
- W2110588388 title "Clevidipine butyrate: a promising new drug for the management of acute hypertension" @default.
- W2110588388 cites W125638225 @default.
- W2110588388 cites W1510291160 @default.
- W2110588388 cites W1567698748 @default.
- W2110588388 cites W1886050967 @default.
- W2110588388 cites W1934161415 @default.
- W2110588388 cites W1949173079 @default.
- W2110588388 cites W1965116881 @default.
- W2110588388 cites W196835504 @default.
- W2110588388 cites W1973274310 @default.
- W2110588388 cites W1982231896 @default.
- W2110588388 cites W1982365774 @default.
- W2110588388 cites W1983692570 @default.
- W2110588388 cites W1988814980 @default.
- W2110588388 cites W1999020491 @default.
- W2110588388 cites W2003193609 @default.
- W2110588388 cites W2011672932 @default.
- W2110588388 cites W2012290498 @default.
- W2110588388 cites W2023515446 @default.
- W2110588388 cites W2023940327 @default.
- W2110588388 cites W2028789442 @default.
- W2110588388 cites W2029476015 @default.
- W2110588388 cites W2030697460 @default.
- W2110588388 cites W2044961796 @default.
- W2110588388 cites W2045596281 @default.
- W2110588388 cites W2052258049 @default.
- W2110588388 cites W2061090938 @default.
- W2110588388 cites W2061462872 @default.
- W2110588388 cites W2068908293 @default.
- W2110588388 cites W2071421281 @default.
- W2110588388 cites W2073599852 @default.
- W2110588388 cites W2078512784 @default.
- W2110588388 cites W2082959447 @default.
- W2110588388 cites W2083359087 @default.
- W2110588388 cites W2085943260 @default.
- W2110588388 cites W2111216488 @default.
- W2110588388 cites W2114634962 @default.
- W2110588388 cites W2121611288 @default.
- W2110588388 cites W2122765407 @default.
- W2110588388 cites W2132647859 @default.
- W2110588388 cites W2133682907 @default.
- W2110588388 cites W2134422033 @default.
- W2110588388 cites W2134997471 @default.
- W2110588388 cites W2139186924 @default.
- W2110588388 cites W2143954917 @default.
- W2110588388 cites W2145422299 @default.
- W2110588388 cites W2155640566 @default.
- W2110588388 cites W2158115528 @default.
- W2110588388 cites W2167067046 @default.
- W2110588388 cites W2167854849 @default.
- W2110588388 cites W2170461036 @default.
- W2110588388 cites W2272106152 @default.
- W2110588388 cites W2314684066 @default.
- W2110588388 cites W2318174853 @default.
- W2110588388 cites W2324185390 @default.
- W2110588388 cites W2915661845 @default.
- W2110588388 cites W3189231122 @default.
- W2110588388 cites W4230013122 @default.
- W2110588388 cites W4231511142 @default.
- W2110588388 cites W4234350910 @default.
- W2110588388 cites W4246338228 @default.
- W2110588388 cites W4248553840 @default.
- W2110588388 doi "https://doi.org/10.1517/14656560903499293" @default.
- W2110588388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20088748" @default.
- W2110588388 hasPublicationYear "2010" @default.
- W2110588388 type Work @default.
- W2110588388 sameAs 2110588388 @default.
- W2110588388 citedByCount "13" @default.
- W2110588388 countsByYear W21105883882012 @default.
- W2110588388 countsByYear W21105883882013 @default.
- W2110588388 countsByYear W21105883882014 @default.
- W2110588388 countsByYear W21105883882016 @default.
- W2110588388 countsByYear W21105883882017 @default.
- W2110588388 countsByYear W21105883882018 @default.
- W2110588388 countsByYear W21105883882020 @default.
- W2110588388 countsByYear W21105883882022 @default.
- W2110588388 crossrefType "journal-article" @default.
- W2110588388 hasAuthorship W2110588388A5015812178 @default.
- W2110588388 hasAuthorship W2110588388A5039382366 @default.
- W2110588388 hasConcept C111113717 @default.
- W2110588388 hasConcept C112705442 @default.
- W2110588388 hasConcept C126322002 @default.
- W2110588388 hasConcept C177713679 @default.
- W2110588388 hasConcept C2780035454 @default.
- W2110588388 hasConcept C2781212610 @default.
- W2110588388 hasConcept C42219234 @default.
- W2110588388 hasConcept C519063684 @default.
- W2110588388 hasConcept C71924100 @default.
- W2110588388 hasConcept C84393581 @default.
- W2110588388 hasConcept C98274493 @default.
- W2110588388 hasConceptScore W2110588388C111113717 @default.
- W2110588388 hasConceptScore W2110588388C112705442 @default.