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• W2110588792 abstract "The necrotrophic pathogen Gibberella pulicaris infects potato tubers through wounds that contain fungitoxic secondary metabolites such as the phytoalexins rishitin and lubimin. In order to colonize tuber tissue, the fungus must possess a mechanism to tolerate potato defense compounds. In this paper, we show that a gene, Gpabc1, that codes an ATP-binding cassette (ABC) transporter is required for tolerance to these phytoalexins and for virulence on potato. The Gpabc1 gene, isolated in the course of a differential cDNA screen, shares high sequence homology with the ABC1 gene of Magnaporthe grisea. G. pulicaris mutants deficient in Gpabc1 were still able to metabolize rishitin but lost their tolerance to this phytoalexin as well as their virulence on potato. These results strongly suggest that the Gpabc1-encoded ABC transporter is necessary for tolerance of G. pulicaris to rishitin and that this tolerance is required for virulence on potato." @default.
• W2110588792 created "2016-06-24" @default.
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• W2110588792 creator A5034414969 @default.
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• W2110588792 date "2002-02-01" @default.
• W2110588792 modified "2023-10-15" @default.
• W2110588792 title "An ATP-binding Cassette Multidrug-Resistance Transporter Is Necessary for Tolerance of <i>Gibberella pulicaris</i> to Phytoalexins and Virulence on Potato Tubers" @default.
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• W2110588792 doi "https://doi.org/10.1094/mpmi.2002.15.2.102" @default.
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