FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110596109> ?p ?o ?g. }

• W2110596109 endingPage "814" @default.
• W2110596109 startingPage "808" @default.
• W2110596109 abstract "Human clinical projects typically require a priori statistical power analyses. Towards this end, we sought to build a flexible and interactive power analysis tool for microarray studies integrated into our public domain HCE 3.5 software package. We then sought to determine if probe set algorithms or organism type strongly influenced power analysis results.The HCE 3.5 power analysis tool was designed to import any pre-existing Affymetrix microarray project, and interactively test the effects of user-defined definitions of alpha (significance), beta (1-power), sample size and effect size. The tool generates a filter for all probe sets or more focused ontology-based subsets, with or without noise filters that can be used to limit analyses of a future project to appropriately powered probe sets. We studied projects from three organisms (Arabidopsis, rat, human), and three probe set algorithms (MAS5.0, RMA, dChip PM/MM). We found large differences in power results based on probe set algorithm selection and noise filters. RMA provided high sensitivity for low numbers of arrays, but this came at a cost of high false positive results (24% false positive in the human project studied). Our data suggest that a priori power calculations are important for both experimental design in hypothesis testing and hypothesis generation, as well as for the selection of optimized data analysis parameters.The Hierarchical Clustering Explorer 3.5 with the interactive power analysis functions is available at www.cs.umd.edu/hcil/hce or www.cnmcresearch.org/bioinformatics.jseo@cnmcresearch.org" @default.
• W2110596109 created "2016-06-24" @default.
• W2110596109 creator A5012388103 @default.
• W2110596109 creator A5070954626 @default.
• W2110596109 creator A5082896865 @default.
• W2110596109 date "2006-01-17" @default.
• W2110596109 modified "2023-09-27" @default.
• W2110596109 title "An interactive power analysis tool for microarray hypothesis testing and generation" @default.
• W2110596109 cites W1980606567 @default.
• W2110596109 cites W1985062374 @default.
• W2110596109 cites W2037021470 @default.
• W2110596109 cites W2038437697 @default.
• W2110596109 cites W2105324766 @default.
• W2110596109 cites W2109972881 @default.
• W2110596109 cites W2120865735 @default.
• W2110596109 cites W2128909276 @default.
• W2110596109 cites W2132631291 @default.
• W2110596109 cites W2145229405 @default.
• W2110596109 cites W2153342722 @default.
• W2110596109 cites W4230395858 @default.
• W2110596109 cites W4247708450 @default.
• W2110596109 cites W4294107304 @default.
• W2110596109 doi "https://doi.org/10.1093/bioinformatics/btk052" @default.
• W2110596109 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16418236" @default.
• W2110596109 hasPublicationYear "2006" @default.
• W2110596109 type Work @default.
• W2110596109 sameAs 2110596109 @default.
• W2110596109 citedByCount "128" @default.
• W2110596109 countsByYear W21105961092012 @default.
• W2110596109 countsByYear W21105961092013 @default.
• W2110596109 countsByYear W21105961092014 @default.
• W2110596109 countsByYear W21105961092015 @default.
• W2110596109 countsByYear W21105961092016 @default.
• W2110596109 countsByYear W21105961092017 @default.
• W2110596109 countsByYear W21105961092018 @default.
• W2110596109 countsByYear W21105961092019 @default.
• W2110596109 countsByYear W21105961092020 @default.
• W2110596109 countsByYear W21105961092021 @default.
• W2110596109 countsByYear W21105961092022 @default.
• W2110596109 countsByYear W21105961092023 @default.
• W2110596109 crossrefType "journal-article" @default.
• W2110596109 hasAuthorship W2110596109A5012388103 @default.
• W2110596109 hasAuthorship W2110596109A5070954626 @default.
• W2110596109 hasAuthorship W2110596109A5082896865 @default.
• W2110596109 hasBestOaLocation W21105961091 @default.
• W2110596109 hasConcept C105795698 @default.
• W2110596109 hasConcept C106131492 @default.
• W2110596109 hasConcept C111472728 @default.
• W2110596109 hasConcept C11413529 @default.
• W2110596109 hasConcept C115961682 @default.
• W2110596109 hasConcept C124101348 @default.
• W2110596109 hasConcept C129848803 @default.
• W2110596109 hasConcept C138885662 @default.
• W2110596109 hasConcept C154945302 @default.
• W2110596109 hasConcept C177264268 @default.
• W2110596109 hasConcept C178489894 @default.
• W2110596109 hasConcept C199360897 @default.
• W2110596109 hasConcept C2777904410 @default.
• W2110596109 hasConcept C31972630 @default.
• W2110596109 hasConcept C33923547 @default.
• W2110596109 hasConcept C41008148 @default.
• W2110596109 hasConcept C71743495 @default.
• W2110596109 hasConcept C73555534 @default.
• W2110596109 hasConcept C75553542 @default.
• W2110596109 hasConcept C87007009 @default.
• W2110596109 hasConcept C96608239 @default.
• W2110596109 hasConcept C99498987 @default.
• W2110596109 hasConceptScore W2110596109C105795698 @default.
• W2110596109 hasConceptScore W2110596109C106131492 @default.
• W2110596109 hasConceptScore W2110596109C111472728 @default.
• W2110596109 hasConceptScore W2110596109C11413529 @default.
• W2110596109 hasConceptScore W2110596109C115961682 @default.
• W2110596109 hasConceptScore W2110596109C124101348 @default.
• W2110596109 hasConceptScore W2110596109C129848803 @default.
• W2110596109 hasConceptScore W2110596109C138885662 @default.
• W2110596109 hasConceptScore W2110596109C154945302 @default.
• W2110596109 hasConceptScore W2110596109C177264268 @default.
• W2110596109 hasConceptScore W2110596109C178489894 @default.
• W2110596109 hasConceptScore W2110596109C199360897 @default.
• W2110596109 hasConceptScore W2110596109C2777904410 @default.
• W2110596109 hasConceptScore W2110596109C31972630 @default.
• W2110596109 hasConceptScore W2110596109C33923547 @default.
• W2110596109 hasConceptScore W2110596109C41008148 @default.
• W2110596109 hasConceptScore W2110596109C71743495 @default.
• W2110596109 hasConceptScore W2110596109C73555534 @default.
• W2110596109 hasConceptScore W2110596109C75553542 @default.
• W2110596109 hasConceptScore W2110596109C87007009 @default.
• W2110596109 hasConceptScore W2110596109C96608239 @default.
• W2110596109 hasConceptScore W2110596109C99498987 @default.
• W2110596109 hasIssue "7" @default.
• W2110596109 hasLocation W21105961091 @default.
• W2110596109 hasLocation W21105961092 @default.
• W2110596109 hasOpenAccess W2110596109 @default.
• W2110596109 hasPrimaryLocation W21105961091 @default.
• W2110596109 hasRelatedWork W111484 @default.
• W2110596109 hasRelatedWork W1595070017 @default.
• W2110596109 hasRelatedWork W2040441512 @default.
• W2110596109 hasRelatedWork W2041726726 @default.

• next