Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110625305> ?p ?o ?g. }
- W2110625305 endingPage "74" @default.
- W2110625305 startingPage "66" @default.
- W2110625305 abstract "Normal mode analysis plays an important role in relating the conformational dynamics of proteins to their biological function. The subspace iteration method is a numerical procedure for normal mode analysis that has enjoyed widespread success in the structural mechanics community due to its numerical stability and computational efficiency in calculating the lowest normal modes of large systems. Here, we apply the subspace iteration method to proteins to demonstrate its advantageous properties in this area of computational protein science. An effective algorithm for choosing the number of iteration vectors in the method is established, offering a considerable improvement over the original implementation. In the present application, computational time scales linearly with the number of normal modes computed. Additionally, the method lends itself naturally to normal mode analyses of multiple neighboring macromolecular conformations, as demonstrated in a conformational change pathway analysis of adenylate kinase. These properties, together with its computational robustness and intrinsic scalability to multiple processors, render the subspace iteration method an effective and reliable computational approach to protein normal mode analysis. © 2009 Wiley Periodicals, Inc. J Comput Chem 2010" @default.
- W2110625305 created "2016-06-24" @default.
- W2110625305 creator A5021644233 @default.
- W2110625305 creator A5029903707 @default.
- W2110625305 creator A5034755833 @default.
- W2110625305 date "2010-01-15" @default.
- W2110625305 modified "2023-09-23" @default.
- W2110625305 title "The subspace iteration method in protein normal mode analysis" @default.
- W2110625305 cites W1975500237 @default.
- W2110625305 cites W1975569870 @default.
- W2110625305 cites W1979974817 @default.
- W2110625305 cites W1981030933 @default.
- W2110625305 cites W1985678401 @default.
- W2110625305 cites W1989161865 @default.
- W2110625305 cites W1998689980 @default.
- W2110625305 cites W2009737642 @default.
- W2110625305 cites W2013726100 @default.
- W2110625305 cites W2016809145 @default.
- W2110625305 cites W2029667189 @default.
- W2110625305 cites W2032049213 @default.
- W2110625305 cites W2036027259 @default.
- W2110625305 cites W2047266495 @default.
- W2110625305 cites W2057636763 @default.
- W2110625305 cites W2068128475 @default.
- W2110625305 cites W2069920107 @default.
- W2110625305 cites W2073560717 @default.
- W2110625305 cites W2088214345 @default.
- W2110625305 cites W2090685385 @default.
- W2110625305 cites W2093151204 @default.
- W2110625305 cites W2097294533 @default.
- W2110625305 cites W2098905320 @default.
- W2110625305 cites W2101017457 @default.
- W2110625305 cites W2102449622 @default.
- W2110625305 cites W2117686912 @default.
- W2110625305 cites W2121925984 @default.
- W2110625305 cites W2134731229 @default.
- W2110625305 cites W2140040046 @default.
- W2110625305 cites W2142872962 @default.
- W2110625305 cites W2156115459 @default.
- W2110625305 cites W2162166182 @default.
- W2110625305 cites W2163304056 @default.
- W2110625305 cites W2235901111 @default.
- W2110625305 cites W2962884542 @default.
- W2110625305 cites W4233439880 @default.
- W2110625305 cites W4293003482 @default.
- W2110625305 cites W2140222779 @default.
- W2110625305 doi "https://doi.org/10.1002/jcc.21250" @default.
- W2110625305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19408277" @default.
- W2110625305 hasPublicationYear "2010" @default.
- W2110625305 type Work @default.
- W2110625305 sameAs 2110625305 @default.
- W2110625305 citedByCount "16" @default.
- W2110625305 countsByYear W21106253052012 @default.
- W2110625305 countsByYear W21106253052013 @default.
- W2110625305 countsByYear W21106253052014 @default.
- W2110625305 countsByYear W21106253052015 @default.
- W2110625305 countsByYear W21106253052017 @default.
- W2110625305 countsByYear W21106253052018 @default.
- W2110625305 crossrefType "journal-article" @default.
- W2110625305 hasAuthorship W2110625305A5021644233 @default.
- W2110625305 hasAuthorship W2110625305A5029903707 @default.
- W2110625305 hasAuthorship W2110625305A5034755833 @default.
- W2110625305 hasBestOaLocation W21106253052 @default.
- W2110625305 hasConcept C104317684 @default.
- W2110625305 hasConcept C111919701 @default.
- W2110625305 hasConcept C112972136 @default.
- W2110625305 hasConcept C11413529 @default.
- W2110625305 hasConcept C119857082 @default.
- W2110625305 hasConcept C121332964 @default.
- W2110625305 hasConcept C134306372 @default.
- W2110625305 hasConcept C147060835 @default.
- W2110625305 hasConcept C154945302 @default.
- W2110625305 hasConcept C159694833 @default.
- W2110625305 hasConcept C185592680 @default.
- W2110625305 hasConcept C198394728 @default.
- W2110625305 hasConcept C28826006 @default.
- W2110625305 hasConcept C32758168 @default.
- W2110625305 hasConcept C32834561 @default.
- W2110625305 hasConcept C33923547 @default.
- W2110625305 hasConcept C41008148 @default.
- W2110625305 hasConcept C48044578 @default.
- W2110625305 hasConcept C48677424 @default.
- W2110625305 hasConcept C48753275 @default.
- W2110625305 hasConcept C55493867 @default.
- W2110625305 hasConcept C62520636 @default.
- W2110625305 hasConcept C63479239 @default.
- W2110625305 hasConcept C77088390 @default.
- W2110625305 hasConceptScore W2110625305C104317684 @default.
- W2110625305 hasConceptScore W2110625305C111919701 @default.
- W2110625305 hasConceptScore W2110625305C112972136 @default.
- W2110625305 hasConceptScore W2110625305C11413529 @default.
- W2110625305 hasConceptScore W2110625305C119857082 @default.
- W2110625305 hasConceptScore W2110625305C121332964 @default.
- W2110625305 hasConceptScore W2110625305C134306372 @default.
- W2110625305 hasConceptScore W2110625305C147060835 @default.
- W2110625305 hasConceptScore W2110625305C154945302 @default.
- W2110625305 hasConceptScore W2110625305C159694833 @default.
- W2110625305 hasConceptScore W2110625305C185592680 @default.