FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110656103> ?p ?o ?g. }

• W2110656103 endingPage "259" @default.
• W2110656103 startingPage "247" @default.
• W2110656103 abstract "Members of the cys-loop ligand-gated ion channel (cysLGIC) superfamily mediate chemical neurotransmission and are studied extensively as potential targets of drugs used to treat neurological disorders, such as Alzheimer's disease. Insect cys-loop LGICs also have central roles in the nervous system and are targets of highly successful insecticides. Here, we describe the cysLGIC superfamily of the parasitoid wasp, Nasonia vitripennis, which is emerging as a highly useful model organism and is deployed as a biological control of insect pests. The wasp superfamily consists of 26 genes, which is the largest insect cysLGIC superfamily characterized, whereas Drosophila melanogaster, Apis mellifera and Tribolium castaneum have 23, 21 and 24, respectively. As with Apis, Drosophila and Tribolium, Nasonia possesses ion channels predicted to be gated by acetylcholine, gamma-amino butyric acid, glutamate and histamine, as well as orthologues of the Drosophila pH-sensitive chloride channel (pHCl), CG8916 and CG12344. Similar to other insects, wasp cysLGIC diversity is broadened by alternative splicing and RNA A-to-I editing, which may also serve to generate species-specific receptor isoforms. These findings on N. vitripennis enhance our understanding of cysLGIC functional genomics and provide a useful basis for the study of their function in the wasp model, as well as for the development of improved insecticides that spare a major beneficial insect species." @default.
• W2110656103 created "2016-06-24" @default.
• W2110656103 creator A5000049629 @default.
• W2110656103 creator A5024049543 @default.
• W2110656103 creator A5026046918 @default.
• W2110656103 creator A5053484252 @default.
• W2110656103 date "2010-01-20" @default.
• W2110656103 modified "2023-10-14" @default.
• W2110656103 title "The cys-loop ligand-gated ion channel gene superfamily of the parasitoid wasp, Nasonia vitripennis" @default.
• W2110656103 cites W1829316027 @default.
• W2110656103 cites W1970354415 @default.
• W2110656103 cites W1975159135 @default.
• W2110656103 cites W1981857440 @default.
• W2110656103 cites W1982481323 @default.
• W2110656103 cites W1986156509 @default.
• W2110656103 cites W1988582613 @default.
• W2110656103 cites W1989810402 @default.
• W2110656103 cites W1993984710 @default.
• W2110656103 cites W2002965963 @default.
• W2110656103 cites W2005356271 @default.
• W2110656103 cites W2009016290 @default.
• W2110656103 cites W2010316537 @default.
• W2110656103 cites W2012829543 @default.
• W2110656103 cites W2023049892 @default.
• W2110656103 cites W2027473126 @default.
• W2110656103 cites W2028939859 @default.
• W2110656103 cites W2038090020 @default.
• W2110656103 cites W2039502494 @default.
• W2110656103 cites W2040264716 @default.
• W2110656103 cites W2049722290 @default.
• W2110656103 cites W2054159696 @default.
• W2110656103 cites W2055043387 @default.
• W2110656103 cites W2057761743 @default.
• W2110656103 cites W2058427270 @default.
• W2110656103 cites W2060232103 @default.
• W2110656103 cites W2060287150 @default.
• W2110656103 cites W2065080767 @default.
• W2110656103 cites W2068530405 @default.
• W2110656103 cites W2068852761 @default.
• W2110656103 cites W2069409086 @default.
• W2110656103 cites W2075214275 @default.
• W2110656103 cites W2076995634 @default.
• W2110656103 cites W2081602909 @default.
• W2110656103 cites W2088241959 @default.
• W2110656103 cites W2088814430 @default.
• W2110656103 cites W2092457589 @default.
• W2110656103 cites W2093912953 @default.
• W2110656103 cites W2097382368 @default.
• W2110656103 cites W2099352796 @default.
• W2110656103 cites W2099810999 @default.
• W2110656103 cites W2104469205 @default.
• W2110656103 cites W2105334068 @default.
• W2110656103 cites W2111622691 @default.
• W2110656103 cites W2116445007 @default.
• W2110656103 cites W2120250745 @default.
• W2110656103 cites W2125865118 @default.
• W2110656103 cites W2135783501 @default.
• W2110656103 cites W2136185611 @default.
• W2110656103 cites W2137543152 @default.
• W2110656103 cites W2145763083 @default.
• W2110656103 cites W2147749026 @default.
• W2110656103 cites W2148926520 @default.
• W2110656103 cites W2154197432 @default.
• W2110656103 cites W2161746138 @default.
• W2110656103 cites W61978249 @default.
• W2110656103 cites W74131495 @default.
• W2110656103 doi "https://doi.org/10.1038/hdy.2009.97" @default.
• W2110656103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20087392" @default.
• W2110656103 hasPublicationYear "2010" @default.
• W2110656103 type Work @default.
• W2110656103 sameAs 2110656103 @default.
• W2110656103 citedByCount "63" @default.
• W2110656103 countsByYear W21106561032012 @default.
• W2110656103 countsByYear W21106561032013 @default.
• W2110656103 countsByYear W21106561032014 @default.
• W2110656103 countsByYear W21106561032015 @default.
• W2110656103 countsByYear W21106561032016 @default.
• W2110656103 countsByYear W21106561032017 @default.
• W2110656103 countsByYear W21106561032018 @default.
• W2110656103 countsByYear W21106561032019 @default.
• W2110656103 countsByYear W21106561032020 @default.
• W2110656103 countsByYear W21106561032021 @default.
• W2110656103 countsByYear W21106561032022 @default.
• W2110656103 countsByYear W21106561032023 @default.
• W2110656103 crossrefType "journal-article" @default.
• W2110656103 hasAuthorship W2110656103A5000049629 @default.
• W2110656103 hasAuthorship W2110656103A5024049543 @default.
• W2110656103 hasAuthorship W2110656103A5026046918 @default.
• W2110656103 hasAuthorship W2110656103A5053484252 @default.
• W2110656103 hasBestOaLocation W21106561031 @default.
• W2110656103 hasConcept C104317684 @default.
• W2110656103 hasConcept C126831891 @default.
• W2110656103 hasConcept C2776998849 @default.
• W2110656103 hasConcept C2777380499 @default.
• W2110656103 hasConcept C2778260489 @default.
• W2110656103 hasConcept C2780104201 @default.
• W2110656103 hasConcept C2780176491 @default.
• W2110656103 hasConcept C2780541402 @default.

• next