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• W2110705364 abstract "The amine metabolites HVA and 5-HIAA in the lumbar CSF of 15 patients with Huntington9s chorea were determined. A negative correlation was found between the severity of symptoms and the CSF HVA, but not 5-HIAA levels. The mean HVA concentration was lower than that of a group of patients with miscellaneous neurological disorders, similar to that of a group with miscellaneous psychiatric disorders and higher than that of a group with Parkinson9s disease. The mean 5-HIAA concentration was similar to that of the neurological group and higher than those of the groups with psychiatric disorders or Parkinson9s disease. CSF HVA and 5-HIAA concentrations of a single patient with severe akinetic rigid Huntington9s chorea were similar to those found in Parkinson9s disease. The findings are discussed in relation to previous neuropathological observations and to reported effects of drugs on the choreic symptoms." @default.
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• W2110705364 date "1972-08-01" @default.
• W2110705364 modified "2023-10-16" @default.
• W2110705364 title "Amine metabolites in the cerebrospinal fluid in Huntington's chorea" @default.
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• W2110705364 doi "https://doi.org/10.1136/jnnp.35.4.514" @default.
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