FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110770237> ?p ?o ?g. }

• W2110770237 endingPage "1415" @default.
• W2110770237 startingPage "1406" @default.
• W2110770237 abstract "Steroid hormones alter dendritic architecture in many animals, but the exact relationship between dendritic anatomy, synaptic strength, and behavioral expression is typically unknown. In larvae of the moth<i>Manduca sexta</i>, the tip of each abdominal proleg (locomotory appendage) bears an array of mechanosensory hairs, each innervated by a planta hair sensory neuron (PH-SN). In the CNS, PH-SN axons make monosynaptic, excitatory nicotinic cholinergic connections with accessory planta retractor (APR) motoneurons. These synapses mediate a proleg withdrawal reflex behavior that is lost at pupation. The prepupal peak of ecdysteroids (molting hormones) triggers the regression of APR dendrites and a >80% reduction in the amplitude of EPSPs produced in APRs by PH-SNs that innervate posterior planta hairs. The present study tested the hypothesis that a decrease in the number of synaptic contacts from PH-SNs to APRs contributes to this synaptic weakening. Pairs of PH-SNs and APRs were fluorescently labeled in larvae and pupae, and the number of indistinguishably close anatomical contacts (putative synapses) was counted by confocal laser scanning microscopy. During APR dendritic regression, the mean number of contacts from posterior PH-SNs decreased by ∼80%, whereas the size of individual contacts did not change detectably and the axonal arbors of PH-SNs did not regress. These results suggest that the steroid-induced regression of motoneuron dendrites physically disconnects the motoneurons from the synaptic terminals of sensory neurons, producing synaptic weakening and the developmental loss of the proleg withdrawal reflex behavior at pupation." @default.
• W2110770237 created "2016-06-24" @default.
• W2110770237 creator A5013874543 @default.
• W2110770237 creator A5017440324 @default.
• W2110770237 date "2003-02-15" @default.
• W2110770237 modified "2023-10-11" @default.
• W2110770237 title "Steroid-Induced Dendritic Regression Reduces Anatomical Contacts between Neurons during Synaptic Weakening and the Developmental Loss of a Behavior" @default.
• W2110770237 cites W1480804537 @default.
• W2110770237 cites W1501825631 @default.
• W2110770237 cites W1519058319 @default.
• W2110770237 cites W1588885232 @default.
• W2110770237 cites W1617822148 @default.
• W2110770237 cites W1618300553 @default.
• W2110770237 cites W1643041936 @default.
• W2110770237 cites W1643861786 @default.
• W2110770237 cites W1672797979 @default.
• W2110770237 cites W1778816614 @default.
• W2110770237 cites W1872002431 @default.
• W2110770237 cites W1919383665 @default.
• W2110770237 cites W1936363472 @default.
• W2110770237 cites W1936601408 @default.
• W2110770237 cites W1974629262 @default.
• W2110770237 cites W1981816303 @default.
• W2110770237 cites W1982648298 @default.
• W2110770237 cites W1990909915 @default.
• W2110770237 cites W1990987108 @default.
• W2110770237 cites W1991474401 @default.
• W2110770237 cites W1996667777 @default.
• W2110770237 cites W2000446528 @default.
• W2110770237 cites W2002787842 @default.
• W2110770237 cites W2003415340 @default.
• W2110770237 cites W2006268333 @default.
• W2110770237 cites W2011301711 @default.
• W2110770237 cites W2017111453 @default.
• W2110770237 cites W2019219547 @default.
• W2110770237 cites W2033232986 @default.
• W2110770237 cites W2034685321 @default.
• W2110770237 cites W2036226222 @default.
• W2110770237 cites W2048672860 @default.
• W2110770237 cites W2049593208 @default.
• W2110770237 cites W2061003322 @default.
• W2110770237 cites W2065912927 @default.
• W2110770237 cites W2067549660 @default.
• W2110770237 cites W2074608263 @default.
• W2110770237 cites W2078458169 @default.
• W2110770237 cites W2083041044 @default.
• W2110770237 cites W2085684814 @default.
• W2110770237 cites W2092194262 @default.
• W2110770237 cites W2099441089 @default.
• W2110770237 cites W2102122262 @default.
• W2110770237 cites W2105735679 @default.
• W2110770237 cites W2106349285 @default.
• W2110770237 cites W2119644933 @default.
• W2110770237 cites W2147565105 @default.
• W2110770237 cites W2241961096 @default.
• W2110770237 cites W2253928272 @default.
• W2110770237 cites W2414203768 @default.
• W2110770237 cites W2439989598 @default.
• W2110770237 doi "https://doi.org/10.1523/jneurosci.23-04-01406.2003" @default.
• W2110770237 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6742267" @default.
• W2110770237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12598629" @default.
• W2110770237 hasPublicationYear "2003" @default.
• W2110770237 type Work @default.
• W2110770237 sameAs 2110770237 @default.
• W2110770237 citedByCount "12" @default.
• W2110770237 countsByYear W21107702372013 @default.
• W2110770237 crossrefType "journal-article" @default.
• W2110770237 hasAuthorship W2110770237A5013874543 @default.
• W2110770237 hasAuthorship W2110770237A5017440324 @default.
• W2110770237 hasBestOaLocation W21107702371 @default.
• W2110770237 hasConcept C105702510 @default.
• W2110770237 hasConcept C112592302 @default.
• W2110770237 hasConcept C169760540 @default.
• W2110770237 hasConcept C17077164 @default.
• W2110770237 hasConcept C18903297 @default.
• W2110770237 hasConcept C22885893 @default.
• W2110770237 hasConcept C2776752467 @default.
• W2110770237 hasConcept C2777240379 @default.
• W2110770237 hasConcept C2777612826 @default.
• W2110770237 hasConcept C2780312687 @default.
• W2110770237 hasConcept C2780775167 @default.
• W2110770237 hasConcept C83974742 @default.
• W2110770237 hasConcept C86803240 @default.
• W2110770237 hasConcept C94487597 @default.
• W2110770237 hasConceptScore W2110770237C105702510 @default.
• W2110770237 hasConceptScore W2110770237C112592302 @default.
• W2110770237 hasConceptScore W2110770237C169760540 @default.
• W2110770237 hasConceptScore W2110770237C17077164 @default.
• W2110770237 hasConceptScore W2110770237C18903297 @default.
• W2110770237 hasConceptScore W2110770237C22885893 @default.
• W2110770237 hasConceptScore W2110770237C2776752467 @default.
• W2110770237 hasConceptScore W2110770237C2777240379 @default.
• W2110770237 hasConceptScore W2110770237C2777612826 @default.
• W2110770237 hasConceptScore W2110770237C2780312687 @default.
• W2110770237 hasConceptScore W2110770237C2780775167 @default.
• W2110770237 hasConceptScore W2110770237C83974742 @default.
• W2110770237 hasConceptScore W2110770237C86803240 @default.
• W2110770237 hasConceptScore W2110770237C94487597 @default.

• next