FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110821369> ?p ?o ?g. }

• W2110821369 endingPage "139" @default.
• W2110821369 startingPage "131" @default.
• W2110821369 abstract "The role of mannose-binding lectin (MBL) deficiency (<i>MBL2</i>;<i> XA/O</i> and <i>O/O</i> genotypes) in host defences remains controversial. The surfactant proteins (SP)-A1, -A2 and -D, other collectins whose genes are located near <i>MBL2</i>, are part of the first-line lung defence against infection. We analysed the role of MBL on susceptibility to pneumococcal infection and the existence of linkage disequilibrium (LD) among the four genes. We studied 348 patients with pneumococcal community-acquired pneumonia (P-CAP) and 2,110 controls. A meta-analysis of <i>MBL2</i> genotypes in susceptibility to P-CAP and to invasive pneumococcal disease (IPD) was also performed. The extent of LD of <i>MBL2</i> with <i>SFTPA1</i>, <i>SFTPA2</i> and <i>SFTPD</i> was analysed. <i>MBL2</i> genotypes did not associate with either P-CAP or bacteraemic P-CAP in the case–control study. The MBL-deficient <i>O/O</i> genotype was significantly associated with higher risk of IPD in a meta-analysis, whereas the other MBL-deficient genotype (<i>XA/O</i>) showed a trend towards a protective role. We showed the existence of LD between <i>MBL2</i> and SP genes. The data do not support a role of MBL deficiency on susceptibility to P-CAP or to IPD. LD among <i>MBL2</i> and SP genes must be considered in studies on the role of MBL in infectious diseases." @default.
• W2110821369 created "2016-06-24" @default.
• W2110821369 creator A5003830997 @default.
• W2110821369 creator A5021433808 @default.
• W2110821369 creator A5025109518 @default.
• W2110821369 creator A5025192546 @default.
• W2110821369 creator A5028120555 @default.
• W2110821369 creator A5032503766 @default.
• W2110821369 creator A5039215759 @default.
• W2110821369 creator A5040943905 @default.
• W2110821369 creator A5042990512 @default.
• W2110821369 creator A5045391024 @default.
• W2110821369 creator A5049006133 @default.
• W2110821369 creator A5055603009 @default.
• W2110821369 creator A5058877192 @default.
• W2110821369 creator A5064547872 @default.
• W2110821369 creator A5074437453 @default.
• W2110821369 creator A5080066902 @default.
• W2110821369 date "2012-04-20" @default.
• W2110821369 modified "2023-10-15" @default.
• W2110821369 title "The role of mannose-binding lectin in pneumococcal infection" @default.
• W2110821369 cites W1544892070 @default.
• W2110821369 cites W1600623361 @default.
• W2110821369 cites W1602188248 @default.
• W2110821369 cites W1942720838 @default.
• W2110821369 cites W1988365133 @default.
• W2110821369 cites W2008308371 @default.
• W2110821369 cites W2015040325 @default.
• W2110821369 cites W2029482690 @default.
• W2110821369 cites W2037306042 @default.
• W2110821369 cites W2037364978 @default.
• W2110821369 cites W2042578578 @default.
• W2110821369 cites W2044106398 @default.
• W2110821369 cites W2052221145 @default.
• W2110821369 cites W2070617252 @default.
• W2110821369 cites W2072398160 @default.
• W2110821369 cites W2076780395 @default.
• W2110821369 cites W2082411276 @default.
• W2110821369 cites W2105147141 @default.
• W2110821369 cites W2105614022 @default.
• W2110821369 cites W2106759155 @default.
• W2110821369 cites W2108855502 @default.
• W2110821369 cites W2121369371 @default.
• W2110821369 cites W2127619636 @default.
• W2110821369 cites W2128457081 @default.
• W2110821369 cites W2132000476 @default.
• W2110821369 cites W2133979383 @default.
• W2110821369 cites W2134394732 @default.
• W2110821369 cites W2139409203 @default.
• W2110821369 cites W2143970440 @default.
• W2110821369 cites W2151051800 @default.
• W2110821369 cites W2171219043 @default.
• W2110821369 cites W2318653171 @default.
• W2110821369 cites W2418616306 @default.
• W2110821369 cites W2428418018 @default.
• W2110821369 doi "https://doi.org/10.1183/09031936.00174111" @default.
• W2110821369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22523362" @default.
• W2110821369 hasPublicationYear "2012" @default.
• W2110821369 type Work @default.
• W2110821369 sameAs 2110821369 @default.
• W2110821369 citedByCount "42" @default.
• W2110821369 countsByYear W21108213692012 @default.
• W2110821369 countsByYear W21108213692013 @default.
• W2110821369 countsByYear W21108213692014 @default.
• W2110821369 countsByYear W21108213692015 @default.
• W2110821369 countsByYear W21108213692016 @default.
• W2110821369 countsByYear W21108213692017 @default.
• W2110821369 countsByYear W21108213692018 @default.
• W2110821369 countsByYear W21108213692019 @default.
• W2110821369 countsByYear W21108213692020 @default.
• W2110821369 countsByYear W21108213692021 @default.
• W2110821369 countsByYear W21108213692022 @default.
• W2110821369 countsByYear W21108213692023 @default.
• W2110821369 crossrefType "journal-article" @default.
• W2110821369 hasAuthorship W2110821369A5003830997 @default.
• W2110821369 hasAuthorship W2110821369A5021433808 @default.
• W2110821369 hasAuthorship W2110821369A5025109518 @default.
• W2110821369 hasAuthorship W2110821369A5025192546 @default.
• W2110821369 hasAuthorship W2110821369A5028120555 @default.
• W2110821369 hasAuthorship W2110821369A5032503766 @default.
• W2110821369 hasAuthorship W2110821369A5039215759 @default.
• W2110821369 hasAuthorship W2110821369A5040943905 @default.
• W2110821369 hasAuthorship W2110821369A5042990512 @default.
• W2110821369 hasAuthorship W2110821369A5045391024 @default.
• W2110821369 hasAuthorship W2110821369A5049006133 @default.
• W2110821369 hasAuthorship W2110821369A5055603009 @default.
• W2110821369 hasAuthorship W2110821369A5058877192 @default.
• W2110821369 hasAuthorship W2110821369A5064547872 @default.
• W2110821369 hasAuthorship W2110821369A5074437453 @default.
• W2110821369 hasAuthorship W2110821369A5080066902 @default.
• W2110821369 hasBestOaLocation W21108213691 @default.
• W2110821369 hasConcept C104317684 @default.
• W2110821369 hasConcept C133493029 @default.
• W2110821369 hasConcept C135763542 @default.
• W2110821369 hasConcept C136449434 @default.
• W2110821369 hasConcept C189413060 @default.
• W2110821369 hasConcept C203014093 @default.
• W2110821369 hasConcept C2777438239 @default.

• next