Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110872024> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2110872024 endingPage "413" @default.
- W2110872024 startingPage "409" @default.
- W2110872024 abstract "In patients who have symptomatic multiple myeloma (MM), a high serum lactate dehydrogenase (LDH) level is associated with features of advanced disease, adds prognostic value to the international staging system (ISS) and predicts for inferior survival. However, it has not been clearly defined what the impact of this abnormality is for patients treated upfront with novel agent-based regimens.To address this issue we analyzed 203 consecutive unselected patients with symptomatic MM who received upfront treatment with novel agents in a single center.The median overall survival for patients with normal LDH was 54 months but in patients with increased LDH levels it was 21 months (P = .003), whereas increased serum LDH was associated with a higher probability of early death. Multivariate analysis confirmed that an increased LDH level is independently associated with poor survival. Furthermore, increased LDH levels could identify subgroups of patients within ISS-2 and ISS-3 with even worse outcome.We conclude that serum LDH is a simple, inexpensive, and readily available blood test that may be included among the variables that define very-high-risk MM." @default.
- W2110872024 created "2016-06-24" @default.
- W2110872024 creator A5007766504 @default.
- W2110872024 creator A5023582747 @default.
- W2110872024 creator A5041407463 @default.
- W2110872024 creator A5044318093 @default.
- W2110872024 creator A5054453797 @default.
- W2110872024 creator A5088691462 @default.
- W2110872024 creator A5090801956 @default.
- W2110872024 creator A5091600816 @default.
- W2110872024 date "2011-10-01" @default.
- W2110872024 modified "2023-10-16" @default.
- W2110872024 title "Increased Serum Lactate Dehydrongenase Should Be Included Among the Variables That Define Very-High-Risk Multiple Myeloma" @default.
- W2110872024 cites W1982530466 @default.
- W2110872024 cites W2011871138 @default.
- W2110872024 cites W2012843756 @default.
- W2110872024 cites W2044436186 @default.
- W2110872024 cites W2045564415 @default.
- W2110872024 cites W2066800926 @default.
- W2110872024 cites W2087843841 @default.
- W2110872024 cites W2095576035 @default.
- W2110872024 cites W2120474651 @default.
- W2110872024 cites W2120549958 @default.
- W2110872024 cites W2126351771 @default.
- W2110872024 cites W2143872632 @default.
- W2110872024 cites W2163999353 @default.
- W2110872024 cites W4252175385 @default.
- W2110872024 doi "https://doi.org/10.1016/j.clml.2011.07.001" @default.
- W2110872024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21903504" @default.
- W2110872024 hasPublicationYear "2011" @default.
- W2110872024 type Work @default.
- W2110872024 sameAs 2110872024 @default.
- W2110872024 citedByCount "39" @default.
- W2110872024 countsByYear W21108720242012 @default.
- W2110872024 countsByYear W21108720242013 @default.
- W2110872024 countsByYear W21108720242014 @default.
- W2110872024 countsByYear W21108720242015 @default.
- W2110872024 countsByYear W21108720242016 @default.
- W2110872024 countsByYear W21108720242017 @default.
- W2110872024 countsByYear W21108720242018 @default.
- W2110872024 countsByYear W21108720242019 @default.
- W2110872024 countsByYear W21108720242021 @default.
- W2110872024 countsByYear W21108720242022 @default.
- W2110872024 countsByYear W21108720242023 @default.
- W2110872024 crossrefType "journal-article" @default.
- W2110872024 hasAuthorship W2110872024A5007766504 @default.
- W2110872024 hasAuthorship W2110872024A5023582747 @default.
- W2110872024 hasAuthorship W2110872024A5041407463 @default.
- W2110872024 hasAuthorship W2110872024A5044318093 @default.
- W2110872024 hasAuthorship W2110872024A5054453797 @default.
- W2110872024 hasAuthorship W2110872024A5088691462 @default.
- W2110872024 hasAuthorship W2110872024A5090801956 @default.
- W2110872024 hasAuthorship W2110872024A5091600816 @default.
- W2110872024 hasConcept C126322002 @default.
- W2110872024 hasConcept C141071460 @default.
- W2110872024 hasConcept C181199279 @default.
- W2110872024 hasConcept C185592680 @default.
- W2110872024 hasConcept C2776364478 @default.
- W2110872024 hasConcept C2777318727 @default.
- W2110872024 hasConcept C2780073493 @default.
- W2110872024 hasConcept C38180746 @default.
- W2110872024 hasConcept C55493867 @default.
- W2110872024 hasConcept C71924100 @default.
- W2110872024 hasConcept C90924648 @default.
- W2110872024 hasConceptScore W2110872024C126322002 @default.
- W2110872024 hasConceptScore W2110872024C141071460 @default.
- W2110872024 hasConceptScore W2110872024C181199279 @default.
- W2110872024 hasConceptScore W2110872024C185592680 @default.
- W2110872024 hasConceptScore W2110872024C2776364478 @default.
- W2110872024 hasConceptScore W2110872024C2777318727 @default.
- W2110872024 hasConceptScore W2110872024C2780073493 @default.
- W2110872024 hasConceptScore W2110872024C38180746 @default.
- W2110872024 hasConceptScore W2110872024C55493867 @default.
- W2110872024 hasConceptScore W2110872024C71924100 @default.
- W2110872024 hasConceptScore W2110872024C90924648 @default.
- W2110872024 hasIssue "5" @default.
- W2110872024 hasLocation W21108720241 @default.
- W2110872024 hasLocation W21108720242 @default.
- W2110872024 hasOpenAccess W2110872024 @default.
- W2110872024 hasPrimaryLocation W21108720241 @default.
- W2110872024 hasRelatedWork W2003938723 @default.
- W2110872024 hasRelatedWork W2047967234 @default.
- W2110872024 hasRelatedWork W2118496982 @default.
- W2110872024 hasRelatedWork W2351986099 @default.
- W2110872024 hasRelatedWork W2364998975 @default.
- W2110872024 hasRelatedWork W2435227317 @default.
- W2110872024 hasRelatedWork W2439875401 @default.
- W2110872024 hasRelatedWork W2610995464 @default.
- W2110872024 hasRelatedWork W4238867864 @default.
- W2110872024 hasRelatedWork W2525756941 @default.
- W2110872024 hasVolume "11" @default.
- W2110872024 isParatext "false" @default.
- W2110872024 isRetracted "false" @default.
- W2110872024 magId "2110872024" @default.
- W2110872024 workType "article" @default.