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- W2110927939 abstract "Alkylation of 1-azafagomine at the 2-N position was achieved by reductive amination of 1-N-acetyl-3,4,6-tri-O-benzyl-1-azafagomine by using aldehydes, palladium hydroxide, and hydrogen in EtOAc/water/acetic acid followed by deprotection. The 2-N-butyl, hexyl, heptyl, nonyl, decyl, and 3-phenylpropyl derivatives were made in this manner, and were tested for inhibition of alpha-glucosidase from yeast, and of beta-glucosidase from almonds. The new compounds were stronger beta-glucosidase inhibitors than 1-azafagomine, but weaker alpha-glucosidase inhibitors." @default.
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- W2110927939 date "2007-04-16" @default.
- W2110927939 modified "2023-10-18" @default.
- W2110927939 title "Anomer-Selective Glycosidase Inhibition by 2-N-Alkylated 1-Azafagomines" @default.
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- W2110927939 doi "https://doi.org/10.1002/cbic.200700012" @default.
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