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- W2110987254 abstract "Objective To evaluate the utility of a transcranial brain photoplethysmography parameter as a potential marker for patients with multiple sclerosis. Methods We investigated 38 patients affected by multiple sclerosis, according to the revised McDonald criteria (12 males and 26 females, mean age 41.1 ± 8.5 years, Expanded Disability Status Scale mean value 2.6 ± 2.1) and compared them with 20 age- and sex-matched healthy controls. By means of transcranial brain photoplethysmography, a safe and non-invasive technology, we measured the increase in cerebral blood volume during compression for 10 s of the internal jugular veins of both sides in sitting position. Results The cerebral blood volume increase was significantly smaller in the multiple sclerosis patients (left frontal cortex: −58%, p < 0.0001; right frontal cortex: −59%, p < 0.0001) compared with the controls. Conclusions Our study reveals that a minor increase in cerebral blood volume on the frontal cortex of both sides in sitting position is associated with a diagnosis of multiple sclerosis and might be a new marker." @default.
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- W2110987254 date "2013-12-13" @default.
- W2110987254 modified "2023-10-18" @default.
- W2110987254 title "Transcranial brain photoplethysmography to study the venules of cerebral cortex in patients with multiple sclerosis" @default.
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- W2110987254 doi "https://doi.org/10.1177/0268355513515650" @default.
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