FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111023425> ?p ?o ?g. }

• W2111023425 endingPage "227" @default.
• W2111023425 startingPage "219" @default.
• W2111023425 abstract "Surface Enhanced Laser Desorption/Ionization Time Of Flight (SELDI-TOF) mass spectrometry is characterized by integration of mass spectrometry with surface chemistry, which gives rise to rapid purification and subsequent determination of protein/peptide analytes. There are several surface matrices, named proteinChips, available for analyzing a particular analyte or a subset of biomolecules in biological samples. Each proteinChip has a unique surface property suitable for fractionation of a specific group of molecules. This article demonstrates the application of SELDI-TOF for the analysis of a cleaved peptide ( M r 7739 daltons) from von Willebrand Factor by a metalloproteinase, ADAMTS13. Deficiency of ADAMTS13 is a known primary risk factor for the devastating hematological disorder, Thrombotic thrombocytopenic purpura (TTP). Rapid determination of ADAMTS13 activity helps clinicians tremendously in making the correct diagnosis and initiating timely therapy. Most patients with TTP are acquired cases who exhibit a production of autoimmune antibodies against ADAMTS13 protease. TTP's clinical course is critically controlled by the autoantibody's ability to inhibit ADAMTS13 function. Thus, a second SELDI-TOF based test has been devised to measure ADAMTS13 autoantibody activity for the evaluation of TTP disease activity. In conclusion, the unique features of SELDI-TOF which allow for the examination of the role of key proteases in disease processes have opened up new doors for the clinical application of mass spectrometer based techniques." @default.
• W2111023425 created "2016-06-24" @default.
• W2111023425 creator A5003125428 @default.
• W2111023425 creator A5012869295 @default.
• W2111023425 creator A5053638396 @default.
• W2111023425 creator A5056228605 @default.
• W2111023425 date "2006-01-01" @default.
• W2111023425 modified "2023-10-17" @default.
• W2111023425 title "Application of SELDI-TOF mass spectrometry in clinical evaluation of thrombotic thrombocytopenic purpura" @default.
• W2111023425 cites W1969804753 @default.
• W2111023425 cites W1976195428 @default.
• W2111023425 cites W1979376741 @default.
• W2111023425 cites W1983594736 @default.
• W2111023425 cites W1984807322 @default.
• W2111023425 cites W1991523524 @default.
• W2111023425 cites W1996856913 @default.
• W2111023425 cites W1998474909 @default.
• W2111023425 cites W2009835186 @default.
• W2111023425 cites W2014003991 @default.
• W2111023425 cites W2014469585 @default.
• W2111023425 cites W2024290100 @default.
• W2111023425 cites W2024773741 @default.
• W2111023425 cites W2030337128 @default.
• W2111023425 cites W2033166984 @default.
• W2111023425 cites W2036263143 @default.
• W2111023425 cites W2036609920 @default.
• W2111023425 cites W2039767677 @default.
• W2111023425 cites W2041065426 @default.
• W2111023425 cites W2042358315 @default.
• W2111023425 cites W2047967564 @default.
• W2111023425 cites W2056427896 @default.
• W2111023425 cites W2059305025 @default.
• W2111023425 cites W2063431502 @default.
• W2111023425 cites W2075302329 @default.
• W2111023425 cites W2077263364 @default.
• W2111023425 cites W2084597906 @default.
• W2111023425 cites W2085290177 @default.
• W2111023425 cites W2086044256 @default.
• W2111023425 cites W2091210046 @default.
• W2111023425 cites W2093312854 @default.
• W2111023425 cites W2095645524 @default.
• W2111023425 cites W2096694969 @default.
• W2111023425 cites W2097563817 @default.
• W2111023425 cites W2100710603 @default.
• W2111023425 cites W2104483045 @default.
• W2111023425 cites W2108639749 @default.
• W2111023425 cites W2108861120 @default.
• W2111023425 cites W2114604545 @default.
• W2111023425 cites W2121859722 @default.
• W2111023425 cites W2136164136 @default.
• W2111023425 cites W2139911580 @default.
• W2111023425 cites W2149568359 @default.
• W2111023425 cites W2151503986 @default.
• W2111023425 cites W2155793022 @default.
• W2111023425 cites W2186521452 @default.
• W2111023425 cites W2225119179 @default.
• W2111023425 cites W2315229770 @default.
• W2111023425 cites W2334213116 @default.
• W2111023425 cites W2340760838 @default.
• W2111023425 cites W2039085612 @default.
• W2111023425 cites W3147102246 @default.
• W2111023425 doi "https://doi.org/10.1155/2006/523702" @default.
• W2111023425 hasPublicationYear "2006" @default.
• W2111023425 type Work @default.
• W2111023425 sameAs 2111023425 @default.
• W2111023425 citedByCount "0" @default.
• W2111023425 crossrefType "journal-article" @default.
• W2111023425 hasAuthorship W2111023425A5003125428 @default.
• W2111023425 hasAuthorship W2111023425A5012869295 @default.
• W2111023425 hasAuthorship W2111023425A5053638396 @default.
• W2111023425 hasAuthorship W2111023425A5056228605 @default.
• W2111023425 hasBestOaLocation W21110234251 @default.
• W2111023425 hasConcept C104317684 @default.
• W2111023425 hasConcept C139883154 @default.
• W2111023425 hasConcept C159654299 @default.
• W2111023425 hasConcept C162356407 @default.
• W2111023425 hasConcept C163764329 @default.
• W2111023425 hasConcept C181199279 @default.
• W2111023425 hasConcept C182220744 @default.
• W2111023425 hasConcept C185592680 @default.
• W2111023425 hasConcept C202157981 @default.
• W2111023425 hasConcept C203014093 @default.
• W2111023425 hasConcept C2778585876 @default.
• W2111023425 hasConcept C2779394231 @default.
• W2111023425 hasConcept C2780921031 @default.
• W2111023425 hasConcept C40684141 @default.
• W2111023425 hasConcept C43617362 @default.
• W2111023425 hasConcept C46111723 @default.
• W2111023425 hasConcept C55493867 @default.
• W2111023425 hasConcept C71924100 @default.
• W2111023425 hasConcept C89560881 @default.
• W2111023425 hasConceptScore W2111023425C104317684 @default.
• W2111023425 hasConceptScore W2111023425C139883154 @default.
• W2111023425 hasConceptScore W2111023425C159654299 @default.
• W2111023425 hasConceptScore W2111023425C162356407 @default.
• W2111023425 hasConceptScore W2111023425C163764329 @default.
• W2111023425 hasConceptScore W2111023425C181199279 @default.
• W2111023425 hasConceptScore W2111023425C182220744 @default.

• next