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- W2111032368 endingPage "946" @default.
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- W2111032368 abstract "Several familial syndromes are associated with an increased incidence of nervous system tumors. Recognition of these syndromes is critical to provide optimal clinical care and genetic counseling to affected patients and their families. Identification of the genetic defects responsible for these relatively uncommon disorders has led to the improved understanding of critical molecular pathways involved in tumorigenesis and has contributed to the emergence of molecularly targeted therapeutics against cancer. The hereditary syndromes and diseases included in this review are limited to those associated with brain tumors: neurofibromatosis 1, neurofibromatosis 2, tuberous sclerosis complex, von Hippel-Lindau disease, and the less frequently encountered Cowden disease and Li-Fraumeni, Turcot's, and Gorlin's syndromes." @default.
- W2111032368 created "2016-06-24" @default.
- W2111032368 creator A5059797681 @default.
- W2111032368 creator A5061164194 @default.
- W2111032368 date "2007-11-01" @default.
- W2111032368 modified "2023-10-17" @default.
- W2111032368 title "Genetic Causes of Brain Tumors: Neurofibromatosis, Tuberous Sclerosis, von Hippel-Lindau, and Other Syndromes" @default.
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- W2111032368 doi "https://doi.org/10.1016/j.ncl.2007.07.008" @default.
- W2111032368 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17964021" @default.
- W2111032368 hasPublicationYear "2007" @default.
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