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- W2111034222 abstract "Drug treatment of patients with functional dyspepsia is controversial but H(2) receptor antagonists have been the mainstay of treatment. For patients with symptoms suggestive of dysmotility, prokinetics such as cisapride have been used. A large number of clinical trials have been unable to produce definite answers as to whether any of these treatment modalities are truly efficacious. This is partly due to the fact that the methodology and reporting of the majority of trials evaluating the symptomatic effects of H(2) receptor antagonists and cisapride are severely flawed. Based on the current literature, H(2) receptor antagonists may possibly have a therapeutic gain of approximately 20% over placebo. Evaluating the therapeutic gain of cisapride is more difficult but meta-analyses indicate a somewhat larger effect." @default.
- W2111034222 created "2016-06-24" @default.
- W2111034222 creator A5016041421 @default.
- W2111034222 date "2002-05-01" @default.
- W2111034222 modified "2023-09-26" @default.
- W2111034222 title "H2 receptor antagonists and prokinetics in dyspepsia: a critical review" @default.
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- W2111034222 doi "https://doi.org/10.1136/gut.50.suppl_4.iv58" @default.
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