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- W2111049062 abstract "Nonketotic hyperglycinemia (NKH) is a rare metabolic brain disease caused by deficient activity of the glycine cleavage system. Localized proton MR spectroscopy (echo-time 166 msec), performed in an infant with the typical clinical and biochemical features of neonatal NKH, showed a markedly increased peak intensity at 3.55 ppm, which was assigned to glycine. Serial proton MR spectroscopic studies indicated that glycine/choline and glycine/total creatine ratios correlated closely with the patient's clinical course. Proton MR spectroscopy was useful for the non-invasive detection and monitoring of cerebral glycine levels in this infant with NKH." @default.
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- W2111049062 date "2001-01-01" @default.
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- W2111049062 title "Localized Proton MR Spectroscopic Detection of Nonketotic Hyperglycinemia in an Infant" @default.
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- W2111049062 doi "https://doi.org/10.3348/kjr.2001.2.4.239" @default.
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