Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111057515> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2111057515 endingPage "987" @default.
- W2111057515 startingPage "973" @default.
- W2111057515 abstract "Flavonoids are secondary products of plants that include thousands of compounds classified in several classes. Preclinical studies mainly carried out in rodents suggest that they may have a role in the prevention of immunoglobulin E (IgE) synthesis and mast cell degranulation. Interestingly, using animal models with allergic asthma, it can be concluded that preventive treatment with particular flavonoid classes can reduce airway hyperresponsiveness, which is accompanied by lowered inflammatory mediators such as histamine and cytokines, and cell infiltration. In addition, there are some clinical trials in patients with allergic asthma or rhinitis that offer promising results with regard to these natural compounds. On the other hand, the dissection of cellular mechanisms that have interacted with flavonoids allow their effectiveness to be understood. Among these mechanisms there is a lower expression of IgE receptor or other membrane receptors, the modulation of calcium influx, and the downregulation of particular signaling pathways that eventually produces lower primary and secondary mediator release. In conclusion, some particular flavonoids could be an alternative or complementary therapy in the prevention and treatment of some allergies. Nevertheless, an increased number of clinical trials is required in order to confirm the therapeutic role of flavonoids." @default.
- W2111057515 created "2016-06-24" @default.
- W2111057515 creator A5017280079 @default.
- W2111057515 creator A5022950298 @default.
- W2111057515 creator A5025274981 @default.
- W2111057515 creator A5039835312 @default.
- W2111057515 date "2014-02-01" @default.
- W2111057515 modified "2023-09-25" @default.
- W2111057515 title "Flavonoids on Allergy" @default.
- W2111057515 doi "https://doi.org/10.2174/13816128113199990041" @default.
- W2111057515 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23701555" @default.
- W2111057515 hasPublicationYear "2014" @default.
- W2111057515 type Work @default.
- W2111057515 sameAs 2111057515 @default.
- W2111057515 citedByCount "30" @default.
- W2111057515 countsByYear W21110575152014 @default.
- W2111057515 countsByYear W21110575152016 @default.
- W2111057515 countsByYear W21110575152017 @default.
- W2111057515 countsByYear W21110575152018 @default.
- W2111057515 countsByYear W21110575152019 @default.
- W2111057515 countsByYear W21110575152020 @default.
- W2111057515 countsByYear W21110575152021 @default.
- W2111057515 countsByYear W21110575152022 @default.
- W2111057515 crossrefType "journal-article" @default.
- W2111057515 hasAuthorship W2111057515A5017280079 @default.
- W2111057515 hasAuthorship W2111057515A5022950298 @default.
- W2111057515 hasAuthorship W2111057515A5025274981 @default.
- W2111057515 hasAuthorship W2111057515A5039835312 @default.
- W2111057515 hasConcept C104317684 @default.
- W2111057515 hasConcept C1122143 @default.
- W2111057515 hasConcept C126322002 @default.
- W2111057515 hasConcept C127561419 @default.
- W2111057515 hasConcept C141105273 @default.
- W2111057515 hasConcept C159654299 @default.
- W2111057515 hasConcept C170493617 @default.
- W2111057515 hasConcept C185592680 @default.
- W2111057515 hasConcept C203014093 @default.
- W2111057515 hasConcept C207480886 @default.
- W2111057515 hasConcept C2776042228 @default.
- W2111057515 hasConcept C2779726688 @default.
- W2111057515 hasConcept C49802076 @default.
- W2111057515 hasConcept C55493867 @default.
- W2111057515 hasConcept C71924100 @default.
- W2111057515 hasConcept C98274493 @default.
- W2111057515 hasConceptScore W2111057515C104317684 @default.
- W2111057515 hasConceptScore W2111057515C1122143 @default.
- W2111057515 hasConceptScore W2111057515C126322002 @default.
- W2111057515 hasConceptScore W2111057515C127561419 @default.
- W2111057515 hasConceptScore W2111057515C141105273 @default.
- W2111057515 hasConceptScore W2111057515C159654299 @default.
- W2111057515 hasConceptScore W2111057515C170493617 @default.
- W2111057515 hasConceptScore W2111057515C185592680 @default.
- W2111057515 hasConceptScore W2111057515C203014093 @default.
- W2111057515 hasConceptScore W2111057515C207480886 @default.
- W2111057515 hasConceptScore W2111057515C2776042228 @default.
- W2111057515 hasConceptScore W2111057515C2779726688 @default.
- W2111057515 hasConceptScore W2111057515C49802076 @default.
- W2111057515 hasConceptScore W2111057515C55493867 @default.
- W2111057515 hasConceptScore W2111057515C71924100 @default.
- W2111057515 hasConceptScore W2111057515C98274493 @default.
- W2111057515 hasIssue "6" @default.
- W2111057515 hasLocation W21110575151 @default.
- W2111057515 hasLocation W21110575152 @default.
- W2111057515 hasOpenAccess W2111057515 @default.
- W2111057515 hasPrimaryLocation W21110575151 @default.
- W2111057515 hasRelatedWork W1571696686 @default.
- W2111057515 hasRelatedWork W1984305696 @default.
- W2111057515 hasRelatedWork W1996833158 @default.
- W2111057515 hasRelatedWork W2040737274 @default.
- W2111057515 hasRelatedWork W2112849484 @default.
- W2111057515 hasRelatedWork W2142119474 @default.
- W2111057515 hasRelatedWork W2800757219 @default.
- W2111057515 hasRelatedWork W2993986613 @default.
- W2111057515 hasRelatedWork W3022562132 @default.
- W2111057515 hasRelatedWork W3028993706 @default.
- W2111057515 hasVolume "20" @default.
- W2111057515 isParatext "false" @default.
- W2111057515 isRetracted "false" @default.
- W2111057515 magId "2111057515" @default.
- W2111057515 workType "article" @default.