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- W2111104518 abstract "A series of new amino functionalized 1,2,4-trioxepanes 8–16 and ester functionalized 1,2,4-trioxepanes 17–19 have been synthesized and evaluated against multi-drug resistant Plasmodium yoelii in Swiss mice. Amino functionalized trioxepanes 14, the most active compound of the series, showed 100% clearance of parasitaemia by oral route on day 4 and 75% protection to the treated mice beyond day 28." @default.
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- W2111104518 date "2008-10-01" @default.
- W2111104518 modified "2023-10-16" @default.
- W2111104518 title "New functionalized 1,2,4-trioxepanes: Synthesis and antimalarial activity against multi-drug resistant P. yoelii in mice" @default.
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- W2111104518 doi "https://doi.org/10.1016/j.bmcl.2008.08.096" @default.
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