FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111122011> ?p ?o ?g. }

• W2111122011 endingPage "A52" @default.
• W2111122011 startingPage "A52" @default.
• W2111122011 abstract "<h3>Introduction</h3> Early inward motion and thickening/thinning of the ventricular septum associated with left bundle branch block (LBBB) is known as the septal flash (SF). Correction of SF corresponds with CRT response. We hypothesise that electromechanical interactions induced by SF are associated with functional changes in conductivity and a “U-shaped” activation pattern. Characterising the spatio-temporal relationship between electrical and mechanical events may explain why patients with a SF respond to CRT. Methods 13 patients (63±10 years, 10 men) with severe heart failure (EF 22.8±5.8%) undergoing CRT underwent echocardiography and non-contact mapping (NCM) pre-implant. Presence and extent of a SF was defined visually and with M-mode and fused with NCM bull′s eye plots of endocardial activation patterns. LV dP/dtmax was measured during different pacing modes. <h3>Results</h3> Five patients had a large SF, four small SF and four no SF. Patients with large SF had areas of conduction block in non-infarcted regions whereas those with small or no SF did not (Abstract 89 figure 1). Patients with large SF had greater acute response to left ventricular (LV) and biventricular (BIV) pacing vs those with small/no SF (% increase dP/dt 28±14% vs 11±19% for LV pacing and 42±28% vs 22±21% for BIV pacing). The lines of conduction block disappeared after LV and BIV pacing, while remaining present with RV pacing (Abstract 89 figure 2). Abstract 89 figure 1 Patient with a large SF. Unipolar isochronal map with NCM electrograms showing fragmented signals (development of split potentials) indicating a reduction of conduction and inability to cross throughout the inferior region. The NCM mapping electrograms show the criteria used by Auricchio et al to define block, with the emergence of R-wave, smallest and earliest at the superior part of the block (where area of block begins) with largest negative peak. Bold white arrows on the electrogram indicate how the electrical activation spreads superiorly in a U-shape pattern leading to the development of split potentials. Abstract 89 figure 2 Activation maps of patient with a large SF. Row A, baseline with area of block and late anterior breakthrough. Row B, RV pacing showing the area of anterior block remains. Row C, BIV pacing. Functional conduction block has disappeared. <h3>Conclusion</h3> A strong interaction exists between electrical activation and mechanical deformation of the septum. Correction of both mechanical synchrony and the functional conduction block by CRT may explain the large positive response in patients with a SF." @default.
• W2111122011 created "2016-06-24" @default.
• W2111122011 creator A5014646978 @default.
• W2111122011 creator A5028325156 @default.
• W2111122011 creator A5031493361 @default.
• W2111122011 creator A5045366490 @default.
• W2111122011 creator A5047904639 @default.
• W2111122011 creator A5049192404 @default.
• W2111122011 creator A5052289283 @default.
• W2111122011 creator A5054797422 @default.
• W2111122011 creator A5056483370 @default.
• W2111122011 creator A5061708179 @default.
• W2111122011 creator A5069248283 @default.
• W2111122011 creator A5070013751 @default.
• W2111122011 creator A5077843387 @default.
• W2111122011 date "2011-06-01" @default.
• W2111122011 modified "2023-09-24" @default.
• W2111122011 title "89 Electromechanical interaction in patients undergoing cardiac resynchronisation therapy: comparison of intracardiac activation maps and early septal contraction in left bundle branch block" @default.
• W2111122011 doi "https://doi.org/10.1136/heartjnl-2011-300198.89" @default.
• W2111122011 hasPublicationYear "2011" @default.
• W2111122011 type Work @default.
• W2111122011 sameAs 2111122011 @default.
• W2111122011 citedByCount "0" @default.
• W2111122011 crossrefType "journal-article" @default.
• W2111122011 hasAuthorship W2111122011A5014646978 @default.
• W2111122011 hasAuthorship W2111122011A5028325156 @default.
• W2111122011 hasAuthorship W2111122011A5031493361 @default.
• W2111122011 hasAuthorship W2111122011A5045366490 @default.
• W2111122011 hasAuthorship W2111122011A5047904639 @default.
• W2111122011 hasAuthorship W2111122011A5049192404 @default.
• W2111122011 hasAuthorship W2111122011A5052289283 @default.
• W2111122011 hasAuthorship W2111122011A5054797422 @default.
• W2111122011 hasAuthorship W2111122011A5056483370 @default.
• W2111122011 hasAuthorship W2111122011A5061708179 @default.
• W2111122011 hasAuthorship W2111122011A5069248283 @default.
• W2111122011 hasAuthorship W2111122011A5070013751 @default.
• W2111122011 hasAuthorship W2111122011A5077843387 @default.
• W2111122011 hasBestOaLocation W21111220111 @default.
• W2111122011 hasConcept C126322002 @default.
• W2111122011 hasConcept C164705383 @default.
• W2111122011 hasConcept C2777233412 @default.
• W2111122011 hasConcept C2777473070 @default.
• W2111122011 hasConcept C2778198053 @default.
• W2111122011 hasConcept C2780040984 @default.
• W2111122011 hasConcept C2780350126 @default.
• W2111122011 hasConcept C71924100 @default.
• W2111122011 hasConcept C80093799 @default.
• W2111122011 hasConceptScore W2111122011C126322002 @default.
• W2111122011 hasConceptScore W2111122011C164705383 @default.
• W2111122011 hasConceptScore W2111122011C2777233412 @default.
• W2111122011 hasConceptScore W2111122011C2777473070 @default.
• W2111122011 hasConceptScore W2111122011C2778198053 @default.
• W2111122011 hasConceptScore W2111122011C2780040984 @default.
• W2111122011 hasConceptScore W2111122011C2780350126 @default.
• W2111122011 hasConceptScore W2111122011C71924100 @default.
• W2111122011 hasConceptScore W2111122011C80093799 @default.
• W2111122011 hasIssue "Suppl 1" @default.
• W2111122011 hasLocation W21111220111 @default.
• W2111122011 hasOpenAccess W2111122011 @default.
• W2111122011 hasPrimaryLocation W21111220111 @default.
• W2111122011 hasRelatedWork W1412556241 @default.
• W2111122011 hasRelatedWork W1994161321 @default.
• W2111122011 hasRelatedWork W2029561027 @default.
• W2111122011 hasRelatedWork W2051306830 @default.
• W2111122011 hasRelatedWork W2075480329 @default.
• W2111122011 hasRelatedWork W2314702867 @default.
• W2111122011 hasRelatedWork W2344610904 @default.
• W2111122011 hasRelatedWork W2999204693 @default.
• W2111122011 hasRelatedWork W3087831636 @default.
• W2111122011 hasRelatedWork W3165523319 @default.
• W2111122011 hasVolume "97" @default.
• W2111122011 isParatext "false" @default.
• W2111122011 isRetracted "false" @default.
• W2111122011 magId "2111122011" @default.
• W2111122011 workType "article" @default.