FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111180711> ?p ?o ?g. }

• W2111180711 endingPage "3868" @default.
• W2111180711 startingPage "3860" @default.
• W2111180711 abstract "Purpose To determine if escalated radiation dose using hypofractionation significantly reduces biochemical and/or clinical disease failure (BCDF) in men treated primarily for prostate cancer. Patients and Methods Between June 2002 and May 2006, men with favorable- to high-risk prostate cancer were randomly allocated to receive 76 Gy in 38 fractions at 2.0 Gy per fraction (conventional fractionation intensity-modulated radiation therapy [CIMRT]) versus 70.2 Gy in 26 fractions at 2.7 Gy per fraction (hypofractionated IMRT [HIMRT]); the latter was estimated to be equivalent to 84.4 Gy in 2.0 Gy fractions. High-risk patients received long-term androgen deprivation therapy (ADT), and some intermediate-risk patients received short-term ADT. The primary end point was the cumulative incidence of BCDF. Secondarily, toxicity was assessed. Results There were 303 assessable patients with a median follow-up of 68.4 months. No significant differences were seen between the treatment arms in terms of the distribution of patients by clinicopathologic or treatment-related (ADT use and length) factors. The 5-year rates of BCDF were 21.4% (95% CI, 14.8% to 28.7%) for CIMRT and 23.3% (95% CI, 16.4% to 31.0%) for HIMRT (P = .745). There were no statistically significant differences in late toxicity between the arms; however, in subgroup analysis, patients with compromised urinary function before enrollment had significantly worse urinary function after HIMRT. Conclusion The hypofractionation regimen did not result in a significant reduction in BCDF; however, it is delivered in 2.5 fewer weeks. Men with compromised urinary function before treatment may not be ideal candidates for this approach." @default.
• W2111180711 created "2016-06-24" @default.
• W2111180711 creator A5004625690 @default.
• W2111180711 creator A5011241002 @default.
• W2111180711 creator A5017770546 @default.
• W2111180711 creator A5021448310 @default.
• W2111180711 creator A5023976830 @default.
• W2111180711 creator A5035208282 @default.
• W2111180711 creator A5043554307 @default.
• W2111180711 creator A5049646055 @default.
• W2111180711 creator A5060104637 @default.
• W2111180711 creator A5063389942 @default.
• W2111180711 creator A5075320625 @default.
• W2111180711 creator A5084898582 @default.
• W2111180711 date "2013-11-01" @default.
• W2111180711 modified "2023-10-17" @default.
• W2111180711 title "Randomized Trial of Hypofractionated External-Beam Radiotherapy for Prostate Cancer" @default.
• W2111180711 cites W1983228790 @default.
• W2111180711 cites W1987470170 @default.
• W2111180711 cites W1997160205 @default.
• W2111180711 cites W2023807811 @default.
• W2111180711 cites W2025727536 @default.
• W2111180711 cites W2038981426 @default.
• W2111180711 cites W2054899405 @default.
• W2111180711 cites W2056643793 @default.
• W2111180711 cites W2057192900 @default.
• W2111180711 cites W2069367669 @default.
• W2111180711 cites W2071365490 @default.
• W2111180711 cites W2073140442 @default.
• W2111180711 cites W2076965963 @default.
• W2111180711 cites W2081704383 @default.
• W2111180711 cites W2093867637 @default.
• W2111180711 cites W2097228107 @default.
• W2111180711 cites W2103290459 @default.
• W2111180711 cites W2114251516 @default.
• W2111180711 cites W2117584600 @default.
• W2111180711 cites W2118044567 @default.
• W2111180711 cites W2135238404 @default.
• W2111180711 cites W2274851081 @default.
• W2111180711 cites W2993539218 @default.
• W2111180711 cites W4293241248 @default.
• W2111180711 doi "https://doi.org/10.1200/jco.2013.51.1972" @default.
• W2111180711 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3805927" @default.
• W2111180711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24101042" @default.
• W2111180711 hasPublicationYear "2013" @default.
• W2111180711 type Work @default.
• W2111180711 sameAs 2111180711 @default.
• W2111180711 citedByCount "391" @default.
• W2111180711 countsByYear W21111807112013 @default.
• W2111180711 countsByYear W21111807112014 @default.
• W2111180711 countsByYear W21111807112015 @default.
• W2111180711 countsByYear W21111807112016 @default.
• W2111180711 countsByYear W21111807112017 @default.
• W2111180711 countsByYear W21111807112018 @default.
• W2111180711 countsByYear W21111807112019 @default.
• W2111180711 countsByYear W21111807112020 @default.
• W2111180711 countsByYear W21111807112021 @default.
• W2111180711 countsByYear W21111807112022 @default.
• W2111180711 countsByYear W21111807112023 @default.
• W2111180711 crossrefType "journal-article" @default.
• W2111180711 hasAuthorship W2111180711A5004625690 @default.
• W2111180711 hasAuthorship W2111180711A5011241002 @default.
• W2111180711 hasAuthorship W2111180711A5017770546 @default.
• W2111180711 hasAuthorship W2111180711A5021448310 @default.
• W2111180711 hasAuthorship W2111180711A5023976830 @default.
• W2111180711 hasAuthorship W2111180711A5035208282 @default.
• W2111180711 hasAuthorship W2111180711A5043554307 @default.
• W2111180711 hasAuthorship W2111180711A5049646055 @default.
• W2111180711 hasAuthorship W2111180711A5060104637 @default.
• W2111180711 hasAuthorship W2111180711A5063389942 @default.
• W2111180711 hasAuthorship W2111180711A5075320625 @default.
• W2111180711 hasAuthorship W2111180711A5084898582 @default.
• W2111180711 hasBestOaLocation W21111807111 @default.
• W2111180711 hasConcept C121608353 @default.
• W2111180711 hasConcept C126322002 @default.
• W2111180711 hasConcept C126894567 @default.
• W2111180711 hasConcept C141071460 @default.
• W2111180711 hasConcept C168563851 @default.
• W2111180711 hasConcept C203092338 @default.
• W2111180711 hasConcept C2776235491 @default.
• W2111180711 hasConcept C2777899217 @default.
• W2111180711 hasConcept C2780192828 @default.
• W2111180711 hasConcept C2781413609 @default.
• W2111180711 hasConcept C2989005 @default.
• W2111180711 hasConcept C509974204 @default.
• W2111180711 hasConcept C71924100 @default.
• W2111180711 hasConcept C72563966 @default.
• W2111180711 hasConcept C88879693 @default.
• W2111180711 hasConceptScore W2111180711C121608353 @default.
• W2111180711 hasConceptScore W2111180711C126322002 @default.
• W2111180711 hasConceptScore W2111180711C126894567 @default.
• W2111180711 hasConceptScore W2111180711C141071460 @default.
• W2111180711 hasConceptScore W2111180711C168563851 @default.
• W2111180711 hasConceptScore W2111180711C203092338 @default.
• W2111180711 hasConceptScore W2111180711C2776235491 @default.
• W2111180711 hasConceptScore W2111180711C2777899217 @default.
• W2111180711 hasConceptScore W2111180711C2780192828 @default.
• W2111180711 hasConceptScore W2111180711C2781413609 @default.

• next