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• W2111221356 abstract "Abstract The design and elaboration of a series of macrocyclic templates that exhibit a propensity to adopt a β‐strand‐like peptide‐backbone conformation led to potent and selective inhibitors of calpain 2. Macrocycle 1 retarded calcium‐induced opacification in an ovine‐lens culture assay and is a lead compound for the development of a drug for cataract treatment. Cbz=carbobenzyloxy. magnified image" @default.
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• W2111221356 date "2009-01-30" @default.
• W2111221356 modified "2023-10-09" @default.
• W2111221356 title "Molecular Modeling, Synthesis, and Biological Evaluation of Macrocyclic Calpain Inhibitors" @default.
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• W2111221356 doi "https://doi.org/10.1002/anie.200805014" @default.
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