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- W2111307924 endingPage "927" @default.
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- W2111307924 abstract "Following fungal-inoculation, P. vulgaris was found to produce small amounts of 7,4′-dihydroxyisoflavone (daidzein), 7,2′,4′-trihydroxyisoflavone, 7,2′,4′-trihydroxyisoflavanone, (6aR, 11aR)-3,9-dihydroxypterocarpan, and (3R)-7,2′,4′-trihydroxyisoflavan. The structures of the latter four compounds were confirmed by synthesis. The principal pterocarpans isolated were phaseollidin and phaseollin and ORD spectra indicate that these compounds have the same (6aR, 11aR)-configuration as 3,9-dihydroxypterocarpan. A pathway leading to phaseollidin and phaseollin is proposed involving 2′-hydroxylation of daidzein, reduction to the isoflavanone, further reduction, dehydration and cyclization to the pterocarpan, and prenylation to give phaseollidin and then cyclization and dehydrogenation to give phaseollin. No evidence of prenylation at the isoflavone or isoflavanone stage was obtained. The phaseollin metabolite, (6aS, 11aS)-6a-hydroxyphaseollin, was also detected." @default.
- W2111307924 created "2016-06-24" @default.
- W2111307924 creator A5057948553 @default.
- W2111307924 date "1980-01-01" @default.
- W2111307924 modified "2023-10-07" @default.
- W2111307924 title "Phaseollin formation and metabolism in Phaseolus vulgaris" @default.
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- W2111307924 doi "https://doi.org/10.1016/0031-9422(80)85139-9" @default.
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