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- W2111386965 abstract "A 12 year old boy presenting with hypercalcaemia (calcium 3.25 mmol/l) and osteopaenia with multiple osteolytic lesions was found to have acute lymphoblastic leukaemia without lymph-adenopathy or organomegaly. Hypercalcaemia is a rare feature of acute leukaemia, but the patients previously described all show very similar characteristics, which were highlighted in this patient. These include age (10-20 years), severe osteolytic bone lesions, lymphoblastic leukaemia, and normal white cell count with absent or rare circulating blasts. Parathyroid hormone levels were normal in this patient, and response to induction therapy was good. This case demonstrates that acute lymphoblastic leukaemia may present in an atypical form without peripheral blasts but with hypercalcaemia and gross skeletal changes." @default.
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- W2111386965 date "1993-06-01" @default.
- W2111386965 modified "2023-10-10" @default.
- W2111386965 title "Hypercalcaemia and multiple osteolytic lesions in childhood acute lymphoblastic leukaemia" @default.
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- W2111386965 doi "https://doi.org/10.1136/pgmj.69.812.483" @default.
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