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- W2111424239 endingPage "341" @default.
- W2111424239 startingPage "304" @default.
- W2111424239 abstract "SUMMARY N-glycosylation of proteins is one of the most prevalent posttranslational modifications in nature. Accordingly, a pathway with shared commonalities is found in all three domains of life. While excellent model systems have been developed for studying N-glycosylation in both Eukarya and Bacteria , an understanding of this process in Archaea was hampered until recently by a lack of effective molecular tools. However, within the last decade, impressive advances in the study of the archaeal version of this important pathway have been made for halophiles, methanogens, and thermoacidophiles, combining glycan structural information obtained by mass spectrometry with bioinformatic, genetic, biochemical, and enzymatic data. These studies reveal both features shared with the eukaryal and bacterial domains and novel archaeon-specific aspects. Unique features of N-glycosylation in Archaea include the presence of unusual dolichol lipid carriers, the use of a variety of linking sugars that connect the glycan to proteins, the presence of novel sugars as glycan constituents, the presence of two very different N-linked glycans attached to the same protein, and the ability to vary the N-glycan composition under different growth conditions. These advances are the focus of this review, with an emphasis on N-glycosylation pathways in Haloferax , Methanococcus , and Sulfolobus ." @default.
- W2111424239 created "2016-06-24" @default.
- W2111424239 creator A5020545158 @default.
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- W2111424239 creator A5053263882 @default.
- W2111424239 creator A5072539617 @default.
- W2111424239 creator A5089386282 @default.
- W2111424239 date "2014-06-01" @default.
- W2111424239 modified "2023-10-18" @default.
- W2111424239 title "N-Linked Glycosylation in Archaea: a Structural, Functional, and Genetic Analysis" @default.
- W2111424239 cites W1481317112 @default.
- W2111424239 cites W1495098782 @default.
- W2111424239 cites W1519824997 @default.
- W2111424239 cites W1521901796 @default.
- W2111424239 cites W1533225291 @default.
- W2111424239 cites W1533269794 @default.
- W2111424239 cites W1536734046 @default.
- W2111424239 cites W1540000608 @default.
- W2111424239 cites W1541706183 @default.
- W2111424239 cites W1558357934 @default.
- W2111424239 cites W1560642806 @default.
- W2111424239 cites W1570474317 @default.
- W2111424239 cites W1575120775 @default.
- W2111424239 cites W1588330609 @default.
- W2111424239 cites W1590820833 @default.
- W2111424239 cites W167308838 @default.
- W2111424239 cites W1780156870 @default.
- W2111424239 cites W1861531665 @default.
- W2111424239 cites W1958003157 @default.
- W2111424239 cites W1961322092 @default.
- W2111424239 cites W1963537078 @default.
- W2111424239 cites W1964462261 @default.
- W2111424239 cites W1967263371 @default.
- W2111424239 cites W1967438984 @default.
- W2111424239 cites W1969589458 @default.
- W2111424239 cites W1971052106 @default.
- W2111424239 cites W1972375269 @default.
- W2111424239 cites W1972435343 @default.
- W2111424239 cites W1973018374 @default.
- W2111424239 cites W1973978578 @default.
- W2111424239 cites W1975288774 @default.
- W2111424239 cites W1975434365 @default.
- W2111424239 cites W1976055217 @default.
- W2111424239 cites W1977272323 @default.
- W2111424239 cites W1978351897 @default.
- W2111424239 cites W1978750313 @default.
- W2111424239 cites W1981878531 @default.
- W2111424239 cites W1982055990 @default.
- W2111424239 cites W1984646810 @default.
- W2111424239 cites W1985584408 @default.
- W2111424239 cites W1986106933 @default.
- W2111424239 cites W1987317728 @default.
- W2111424239 cites W1987804131 @default.
- W2111424239 cites W1988541630 @default.
- W2111424239 cites W1991069157 @default.
- W2111424239 cites W1994499691 @default.
- W2111424239 cites W1995611711 @default.
- W2111424239 cites W1996201718 @default.
- W2111424239 cites W1996401266 @default.
- W2111424239 cites W1997285024 @default.
- W2111424239 cites W1998536115 @default.
- W2111424239 cites W1998555791 @default.
- W2111424239 cites W1998661098 @default.
- W2111424239 cites W1999172896 @default.
- W2111424239 cites W2001929483 @default.
- W2111424239 cites W2002722201 @default.
- W2111424239 cites W2003895492 @default.
- W2111424239 cites W2004021364 @default.
- W2111424239 cites W2004125187 @default.
- W2111424239 cites W2006005895 @default.
- W2111424239 cites W2006617103 @default.
- W2111424239 cites W2006631610 @default.
- W2111424239 cites W2006673705 @default.
- W2111424239 cites W2007370567 @default.
- W2111424239 cites W2007432405 @default.
- W2111424239 cites W2007588031 @default.
- W2111424239 cites W2007703737 @default.
- W2111424239 cites W2008683693 @default.
- W2111424239 cites W2010773576 @default.
- W2111424239 cites W2010848666 @default.
- W2111424239 cites W2015694105 @default.
- W2111424239 cites W2017323992 @default.
- W2111424239 cites W2019577213 @default.
- W2111424239 cites W2019790752 @default.
- W2111424239 cites W2021121470 @default.
- W2111424239 cites W2021533673 @default.
- W2111424239 cites W2021647924 @default.
- W2111424239 cites W2027390719 @default.
- W2111424239 cites W2028354193 @default.
- W2111424239 cites W2032006741 @default.
- W2111424239 cites W2033319529 @default.
- W2111424239 cites W2034715670 @default.
- W2111424239 cites W2034791373 @default.
- W2111424239 cites W2039473380 @default.
- W2111424239 cites W2040518239 @default.
- W2111424239 cites W2040708926 @default.
- W2111424239 cites W2040953890 @default.