Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111474105> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2111474105 endingPage "335" @default.
- W2111474105 startingPage "330" @default.
- W2111474105 abstract "Although there are plenty of evidence that dysregulation of microRNA (miRNA) level is involved in many human diseases, it is still unknown whether abnormal levels of specific miRNAs are associated with recurrent pregnancy loss (RPL). We believe that such an association do exist as this study confirmed significant differences in the level of specific miRNAs between RPL cases and healthy controls. The study was conducted on 100 Palestinian women: 60 patients with at least two unexplained consecutive pregnancy losses half of them were pregnant at the first trimester and the rest were non-pregnant and 40 healthy controls with at least two live births and no history of pregnancy loss; half of them were at their first trimester of pregnancy and the rest were non-pregnant. We investigated the relative expression of miR-21, miR-126, miR-155, miR-182, miR-222 and miR-517* using quantitative real-time polymerase chain reaction and Ct method experiments. Differential expression was evaluated using Student t-test and fold change analyses. The expression difference of miR-21, miR-126 and miR-182 between patients and controls in the pregnant subjects showed statistically significant difference (p-value ≤ 0.05) with fold decrease of 1.5, 1.6 and 5.6, respectively. In the non-pregnant group miR-21, miR-126, miR-222 and miR-517* expressions were significantly different with fold decrease of 2.4, 2.9, 2.7 and 11.8, respectively. In conclusion, at least miR-21 and miR-126 could serve as potential markers for idiopathic RPL as their levels were significantly lower in patients before being pregnant and during pregnancy. Moreover, restoration of the normal level of those miRNAs might be a novel intervention strategy in unexplained RPL." @default.
- W2111474105 created "2016-06-24" @default.
- W2111474105 creator A5082994633 @default.
- W2111474105 creator A5087354154 @default.
- W2111474105 date "2013-01-01" @default.
- W2111474105 modified "2023-09-26" @default.
- W2111474105 title "Dysregulation of micro-RNA contributes to the risk of unexplained recurrent pregnancy loss" @default.
- W2111474105 cites W1493066653 @default.
- W2111474105 cites W156007080 @default.
- W2111474105 cites W1974307668 @default.
- W2111474105 cites W1975955509 @default.
- W2111474105 cites W1979898204 @default.
- W2111474105 cites W1982573088 @default.
- W2111474105 cites W1993474041 @default.
- W2111474105 cites W1996137961 @default.
- W2111474105 cites W2000093333 @default.
- W2111474105 cites W2002917664 @default.
- W2111474105 cites W2002995168 @default.
- W2111474105 cites W2010461414 @default.
- W2111474105 cites W2015681531 @default.
- W2111474105 cites W2036961190 @default.
- W2111474105 cites W2045406164 @default.
- W2111474105 cites W2046223396 @default.
- W2111474105 cites W2046710525 @default.
- W2111474105 cites W2053696952 @default.
- W2111474105 cites W2057929910 @default.
- W2111474105 cites W2062510271 @default.
- W2111474105 cites W2087452029 @default.
- W2111474105 cites W2098043285 @default.
- W2111474105 cites W2111778724 @default.
- W2111474105 cites W2125117632 @default.
- W2111474105 cites W2128674168 @default.
- W2111474105 cites W2137385355 @default.
- W2111474105 cites W2140819420 @default.
- W2111474105 cites W2146236251 @default.
- W2111474105 cites W2146864915 @default.
- W2111474105 cites W2153243877 @default.
- W2111474105 cites W2156554003 @default.
- W2111474105 cites W2165031064 @default.
- W2111474105 cites W26434078 @default.
- W2111474105 doi "https://doi.org/10.5455/2320-1770.ijrcog20130914" @default.
- W2111474105 hasPublicationYear "2013" @default.
- W2111474105 type Work @default.
- W2111474105 sameAs 2111474105 @default.
- W2111474105 citedByCount "7" @default.
- W2111474105 countsByYear W21114741052015 @default.
- W2111474105 countsByYear W21114741052017 @default.
- W2111474105 countsByYear W21114741052018 @default.
- W2111474105 countsByYear W21114741052022 @default.
- W2111474105 crossrefType "journal-article" @default.
- W2111474105 hasAuthorship W2111474105A5082994633 @default.
- W2111474105 hasAuthorship W2111474105A5087354154 @default.
- W2111474105 hasConcept C131872663 @default.
- W2111474105 hasConcept C2779234561 @default.
- W2111474105 hasConcept C54355233 @default.
- W2111474105 hasConcept C71924100 @default.
- W2111474105 hasConcept C86803240 @default.
- W2111474105 hasConceptScore W2111474105C131872663 @default.
- W2111474105 hasConceptScore W2111474105C2779234561 @default.
- W2111474105 hasConceptScore W2111474105C54355233 @default.
- W2111474105 hasConceptScore W2111474105C71924100 @default.
- W2111474105 hasConceptScore W2111474105C86803240 @default.
- W2111474105 hasLocation W21114741051 @default.
- W2111474105 hasOpenAccess W2111474105 @default.
- W2111474105 hasPrimaryLocation W21114741051 @default.
- W2111474105 hasRelatedWork W2109994796 @default.
- W2111474105 hasRelatedWork W2273956082 @default.
- W2111474105 hasRelatedWork W2363400180 @default.
- W2111474105 hasRelatedWork W2391778245 @default.
- W2111474105 hasRelatedWork W2401739700 @default.
- W2111474105 hasRelatedWork W2413530964 @default.
- W2111474105 hasRelatedWork W2558155956 @default.
- W2111474105 hasRelatedWork W2614365095 @default.
- W2111474105 hasRelatedWork W2783428915 @default.
- W2111474105 hasRelatedWork W3187277275 @default.
- W2111474105 isParatext "false" @default.
- W2111474105 isRetracted "false" @default.
- W2111474105 magId "2111474105" @default.
- W2111474105 workType "article" @default.