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- W2111475684 abstract "A series of new 2-aryl-4-thiazolidinones (3 and 4) was synthesized from 2-hydroxy-2,2-diphenyl-N’-[(substituted phenyl)methylene]acetohydrazides (2) and mercaptoacetic acid or 2-mercaptopropionic acid. The antimycobacterial activity of these compounds was determined and several leads with 95–99% inhibition at 6.25 μg/mL test concentration were identified. In addition, antitumor activities were measured against several tumor cell lines, and significant growth inhibition was observed for compound 4p. Taken together, 2-aryl-4-thiazolidinones were shown to be promising scaffolds for both antimycobacterial and tumor-targeting compounds." @default.
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- W2111475684 date "2009-07-22" @default.
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- W2111475684 title "Synthesis and biological evaluation of new 4-thiazolidinone derivatives" @default.
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- W2111475684 doi "https://doi.org/10.1080/14756360802608021" @default.
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