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- W2111480605 abstract "Chemoenzymatic Synthesis of 13C-Labeled S-(-)-Malic Acid The first regio- and stereospecific synthesis of S-(-)-13C-malic acid 5 with a high incorporation of 13C and excellent enantiomeric excess is described. S-(-)-13C-malic acid 5 was synthesized in a three-step reaction starting with ethyl acetate 2 and diethyl oxalate 1. The produced sodium diethyl oxaloacetate 3 was then enantioselectively reduced with bakers' yeast to S-(-)-13C-malic acid diethylester 4 which was hydrolyzed to S-(-)-13C-malic acid 5." @default.
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- W2111480605 date "1993-01-01" @default.
- W2111480605 modified "2023-09-25" @default.
- W2111480605 title "Chemoenzymatische Synthese von13C-markierter S-(-)-�pfels�ure" @default.
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- W2111480605 doi "https://doi.org/10.1002/prac.19933350405" @default.
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