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• W2111482014 abstract "The removal of excess free cholesterol from cells by HDL or its apolipoproteins is important for maintaining cellular cholesterol homeostasis. This process is most likely compromised in the atherosclerotic lesion because the development of atherosclerosis is associated with low HDL cholesterol. Multiple mechanisms for efflux of cell cholesterol exist. Efflux of free cholesterol via aqueous diffusion occurs with all cell types but is inefficient. Efflux of cholesterol is accelerated when scavenger receptor class-B type I (SR-BI) is present in the cell plasma membrane. Both diffusion-mediated and SR-BI-mediated efflux occur to phospholipid-containing acceptors (ie, HDL and lipidated apolipoproteins); in both cases, the flux of cholesterol is bidirectional, with the direction of net flux depending on the cholesterol gradient. The ATP-binding cassette transporter AI (ABCA1) mediates efflux of both cellular cholesterol and phospholipid. In contrast to SR-BI-mediated flux, efflux via ABCA1 is unidirectional, occurring to lipid-poor apolipoproteins. The relative importance of the SR-BI and ABCA1 efflux pathways in preventing the development of atherosclerotic plaque is not known but will depend on the expression levels of the two proteins and on the type of cholesterol acceptors available." @default.
• W2111482014 created "2016-06-24" @default.
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• W2111482014 date "2003-05-01" @default.
• W2111482014 modified "2023-10-14" @default.
• W2111482014 title "Importance of Different Pathways of Cellular Cholesterol Efflux" @default.
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• W2111482014 cites W1591670239 @default.
• W2111482014 cites W1594886649 @default.
• W2111482014 cites W1607399348 @default.
• W2111482014 cites W1860908381 @default.
• W2111482014 cites W1908587496 @default.
• W2111482014 cites W1966609176 @default.
• W2111482014 cites W1967468249 @default.
• W2111482014 cites W1969110010 @default.
• W2111482014 cites W1973195548 @default.
• W2111482014 cites W1974176003 @default.
• W2111482014 cites W1974864595 @default.
• W2111482014 cites W1986439388 @default.
• W2111482014 cites W1986963574 @default.
• W2111482014 cites W1987697559 @default.
• W2111482014 cites W1990585451 @default.
• W2111482014 cites W1993028907 @default.
• W2111482014 cites W1993447679 @default.
• W2111482014 cites W2009636256 @default.
• W2111482014 cites W2009832539 @default.
• W2111482014 cites W2013282518 @default.
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• W2111482014 cites W2017443346 @default.
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• W2111482014 cites W2024131238 @default.
• W2111482014 cites W2032350462 @default.
• W2111482014 cites W2032513433 @default.
• W2111482014 cites W2035780860 @default.
• W2111482014 cites W2037131341 @default.
• W2111482014 cites W2040149610 @default.
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• W2111482014 cites W2048397414 @default.
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• W2111482014 doi "https://doi.org/10.1161/01.atv.0000057572.97137.dd" @default.
• W2111482014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12615688" @default.
• W2111482014 hasPublicationYear "2003" @default.
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