FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111486148> ?p ?o ?g. }

• W2111486148 endingPage "53" @default.
• W2111486148 startingPage "4948" @default.
• W2111486148 abstract "The reactivity of a panel of antiganglioside monoclonal antibodies with a number of melanoma cell lines having different ganglioside composition profiles was studied. One cell line synthesized only GM3, one produced both GM3 and GD2, 2 had GM3 and GD3 as their major gangliosides, and 2 others synthesized approximately equal amounts of GM3, GM2, GD3, and GD2 gangliosides. Antibody reactivity with viable cells was analyzed by: (a) flow cytometry on suspension cells; and (b) mixed hemagglutination assays or immune adherence assays on monolayer cells in culture. GM3 was efficiently detected only in the cell line having GM3 as its sole ganglioside. In the other cell lines, GM3 was difficult to detect even in cells in which it made up a high proportion (up to 50%) of the total ganglioside content. GM2 was easily detectable only in JB-RH melanoma cells (which contain only GM3 and GM2). GD3 was the most reactive ganglioside in 2 cell lines and GD2 in 2 other lines. In general, the most complex ganglioside present in a cell was the one most accessible to antibody. The differential exposure at the cell surface of specific gangliosides may have implications for antibody-directed tumor detection and therapy and for cell-protein or cell-cell interactions that involve glycolipids." @default.
• W2111486148 created "2016-06-24" @default.
• W2111486148 creator A5023540371 @default.
• W2111486148 creator A5031921449 @default.
• W2111486148 creator A5050896808 @default.
• W2111486148 creator A5089549568 @default.
• W2111486148 date "1992-09-15" @default.
• W2111486148 modified "2023-09-23" @default.
• W2111486148 title "Cell surface accessibility of individual gangliosides in malignant melanoma cells to antibodies is influenced by the total ganglioside composition of the cells." @default.
• W2111486148 cites W1480374655 @default.
• W2111486148 cites W1486973074 @default.
• W2111486148 cites W1495717648 @default.
• W2111486148 cites W1509074378 @default.
• W2111486148 cites W1520029826 @default.
• W2111486148 cites W1520466764 @default.
• W2111486148 cites W1532637157 @default.
• W2111486148 cites W1546008654 @default.
• W2111486148 cites W1574227588 @default.
• W2111486148 cites W1578547237 @default.
• W2111486148 cites W1601227390 @default.
• W2111486148 cites W1854777117 @default.
• W2111486148 cites W1970244518 @default.
• W2111486148 cites W1985572665 @default.
• W2111486148 cites W2003380411 @default.
• W2111486148 cites W2009885172 @default.
• W2111486148 cites W2016292927 @default.
• W2111486148 cites W2024152313 @default.
• W2111486148 cites W2038585043 @default.
• W2111486148 cites W2051105058 @default.
• W2111486148 cites W2052573499 @default.
• W2111486148 cites W2056509744 @default.
• W2111486148 cites W2060643327 @default.
• W2111486148 cites W2075333800 @default.
• W2111486148 cites W2075836148 @default.
• W2111486148 cites W2084617331 @default.
• W2111486148 cites W2088891603 @default.
• W2111486148 cites W2092810942 @default.
• W2111486148 cites W2096025900 @default.
• W2111486148 cites W2099906887 @default.
• W2111486148 cites W2111838924 @default.
• W2111486148 cites W2116850184 @default.
• W2111486148 cites W2138147234 @default.
• W2111486148 cites W2155118053 @default.
• W2111486148 cites W2344198552 @default.
• W2111486148 cites W2409426515 @default.
• W2111486148 cites W2485306969 @default.
• W2111486148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1516051" @default.
• W2111486148 hasPublicationYear "1992" @default.
• W2111486148 type Work @default.
• W2111486148 sameAs 2111486148 @default.
• W2111486148 citedByCount "21" @default.
• W2111486148 countsByYear W21114861482015 @default.
• W2111486148 countsByYear W21114861482016 @default.
• W2111486148 countsByYear W21114861482023 @default.
• W2111486148 crossrefType "journal-article" @default.
• W2111486148 hasAuthorship W2111486148A5023540371 @default.
• W2111486148 hasAuthorship W2111486148A5031921449 @default.
• W2111486148 hasAuthorship W2111486148A5050896808 @default.
• W2111486148 hasAuthorship W2111486148A5089549568 @default.
• W2111486148 hasConcept C1491633281 @default.
• W2111486148 hasConcept C153911025 @default.
• W2111486148 hasConcept C159654299 @default.
• W2111486148 hasConcept C185592680 @default.
• W2111486148 hasConcept C203014093 @default.
• W2111486148 hasConcept C22222904 @default.
• W2111486148 hasConcept C2777331542 @default.
• W2111486148 hasConcept C542903549 @default.
• W2111486148 hasConcept C54355233 @default.
• W2111486148 hasConcept C553184892 @default.
• W2111486148 hasConcept C55493867 @default.
• W2111486148 hasConcept C81885089 @default.
• W2111486148 hasConcept C86803240 @default.
• W2111486148 hasConceptScore W2111486148C1491633281 @default.
• W2111486148 hasConceptScore W2111486148C153911025 @default.
• W2111486148 hasConceptScore W2111486148C159654299 @default.
• W2111486148 hasConceptScore W2111486148C185592680 @default.
• W2111486148 hasConceptScore W2111486148C203014093 @default.
• W2111486148 hasConceptScore W2111486148C22222904 @default.
• W2111486148 hasConceptScore W2111486148C2777331542 @default.
• W2111486148 hasConceptScore W2111486148C542903549 @default.
• W2111486148 hasConceptScore W2111486148C54355233 @default.
• W2111486148 hasConceptScore W2111486148C553184892 @default.
• W2111486148 hasConceptScore W2111486148C55493867 @default.
• W2111486148 hasConceptScore W2111486148C81885089 @default.
• W2111486148 hasConceptScore W2111486148C86803240 @default.
• W2111486148 hasIssue "18" @default.
• W2111486148 hasLocation W21114861481 @default.
• W2111486148 hasOpenAccess W2111486148 @default.
• W2111486148 hasPrimaryLocation W21114861481 @default.
• W2111486148 hasRelatedWork W1987801792 @default.
• W2111486148 hasRelatedWork W1988955679 @default.
• W2111486148 hasRelatedWork W2009889818 @default.
• W2111486148 hasRelatedWork W2050191099 @default.
• W2111486148 hasRelatedWork W2054851297 @default.
• W2111486148 hasRelatedWork W2087041936 @default.
• W2111486148 hasRelatedWork W2087083440 @default.
• W2111486148 hasRelatedWork W2196101296 @default.
• W2111486148 hasRelatedWork W2368460920 @default.

• next