Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111488679> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2111488679 endingPage "1125" @default.
- W2111488679 startingPage "1120" @default.
- W2111488679 abstract "To identify any preferential or selective migration of T-cell specificities to inflamed tissues of rheumatoid arthritis (RA) patients.Lymphocytes from peripheral blood (PB) and synovial tissue (ST) were isolated from RA patients and stimulated with a panel of crude antigen preparations from 18 bacterial, protozoan and viral sources. Proliferative responses of the T lymphocytes to each antigen and group of antigens were compared in PB and ST. Antigen-specific T-cell clones were developed and their migratory capacities towards synovial chemokines were compared.ST-derived T cells showed a small but significantly higher stimulation index (SI) to the group of intestinal bacteria compared with PB T cells. Conversely, responses of ST-derived T cells to Acanthamoeba polyphaga (AP) were both profoundly and significantly lower compared with PB-derived T cells. The viral antigens as a whole gave comparable reactivities in blood and ST. The migratory capacity of AP-specific T-cell clones towards chemokines produced by ST was profoundly poorer compared with Campylobacter jejuni- and herpes simplex virus-specific T-cell clones.The results indicate a selective migration of T cells of given specificities to the inflamed rheumatoid synovium." @default.
- W2111488679 created "2016-06-24" @default.
- W2111488679 creator A5000560776 @default.
- W2111488679 creator A5015208014 @default.
- W2111488679 creator A5017081376 @default.
- W2111488679 creator A5029735696 @default.
- W2111488679 creator A5046358995 @default.
- W2111488679 creator A5085734972 @default.
- W2111488679 date "2001-10-01" @default.
- W2111488679 modified "2023-10-18" @default.
- W2111488679 title "T‐cell responses to viral, bacterial and protozoan antigens in rheumatoid inflammation. Selective migration of T cells to synovial tissue" @default.
- W2111488679 cites W1535141082 @default.
- W2111488679 cites W1899585915 @default.
- W2111488679 cites W1967547219 @default.
- W2111488679 cites W1974248935 @default.
- W2111488679 cites W1975338541 @default.
- W2111488679 cites W1999905127 @default.
- W2111488679 cites W2005856361 @default.
- W2111488679 cites W2014735918 @default.
- W2111488679 cites W2040725204 @default.
- W2111488679 cites W2058688958 @default.
- W2111488679 cites W2079184949 @default.
- W2111488679 cites W2103384599 @default.
- W2111488679 cites W2113455790 @default.
- W2111488679 cites W2119519960 @default.
- W2111488679 cites W2130562475 @default.
- W2111488679 cites W2132411790 @default.
- W2111488679 cites W2152348310 @default.
- W2111488679 cites W2166075029 @default.
- W2111488679 cites W2315587102 @default.
- W2111488679 cites W4248027597 @default.
- W2111488679 doi "https://doi.org/10.1093/rheumatology/40.10.1120" @default.
- W2111488679 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11600741" @default.
- W2111488679 hasPublicationYear "2001" @default.
- W2111488679 type Work @default.
- W2111488679 sameAs 2111488679 @default.
- W2111488679 citedByCount "11" @default.
- W2111488679 countsByYear W21114886792014 @default.
- W2111488679 countsByYear W21114886792018 @default.
- W2111488679 countsByYear W21114886792020 @default.
- W2111488679 countsByYear W21114886792021 @default.
- W2111488679 countsByYear W21114886792023 @default.
- W2111488679 crossrefType "journal-article" @default.
- W2111488679 hasAuthorship W2111488679A5000560776 @default.
- W2111488679 hasAuthorship W2111488679A5015208014 @default.
- W2111488679 hasAuthorship W2111488679A5017081376 @default.
- W2111488679 hasAuthorship W2111488679A5029735696 @default.
- W2111488679 hasAuthorship W2111488679A5046358995 @default.
- W2111488679 hasAuthorship W2111488679A5085734972 @default.
- W2111488679 hasBestOaLocation W21114886791 @default.
- W2111488679 hasConcept C13373296 @default.
- W2111488679 hasConcept C147483822 @default.
- W2111488679 hasConcept C203014093 @default.
- W2111488679 hasConcept C2776090121 @default.
- W2111488679 hasConcept C2776914184 @default.
- W2111488679 hasConcept C2777575956 @default.
- W2111488679 hasConcept C71924100 @default.
- W2111488679 hasConcept C86803240 @default.
- W2111488679 hasConcept C8891405 @default.
- W2111488679 hasConceptScore W2111488679C13373296 @default.
- W2111488679 hasConceptScore W2111488679C147483822 @default.
- W2111488679 hasConceptScore W2111488679C203014093 @default.
- W2111488679 hasConceptScore W2111488679C2776090121 @default.
- W2111488679 hasConceptScore W2111488679C2776914184 @default.
- W2111488679 hasConceptScore W2111488679C2777575956 @default.
- W2111488679 hasConceptScore W2111488679C71924100 @default.
- W2111488679 hasConceptScore W2111488679C86803240 @default.
- W2111488679 hasConceptScore W2111488679C8891405 @default.
- W2111488679 hasIssue "10" @default.
- W2111488679 hasLocation W21114886791 @default.
- W2111488679 hasLocation W21114886792 @default.
- W2111488679 hasOpenAccess W2111488679 @default.
- W2111488679 hasPrimaryLocation W21114886791 @default.
- W2111488679 hasRelatedWork W2150503314 @default.
- W2111488679 hasRelatedWork W2384738060 @default.
- W2111488679 hasRelatedWork W2416097977 @default.
- W2111488679 hasRelatedWork W2750608465 @default.
- W2111488679 hasRelatedWork W2993678931 @default.
- W2111488679 hasRelatedWork W3045583548 @default.
- W2111488679 hasRelatedWork W4386016105 @default.
- W2111488679 hasRelatedWork W812086887 @default.
- W2111488679 hasRelatedWork W2185550546 @default.
- W2111488679 hasRelatedWork W2289133684 @default.
- W2111488679 hasVolume "40" @default.
- W2111488679 isParatext "false" @default.
- W2111488679 isRetracted "false" @default.
- W2111488679 magId "2111488679" @default.
- W2111488679 workType "article" @default.