FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W21114892> ?p ?o ?g. }

• W21114892 endingPage "6" @default.
• W21114892 startingPage "290" @default.
• W21114892 abstract "To estimate weight and body composition changes during R-CHOP combination therapy in patients with non-Hodgkin's lymphoma (NHL) and their impact on dose intensity (DI) and toxicity.We prospectively evaluated body composition in patients with NHL before starting chemotherapy (visit 1), before the 3rd cycle (visit 2) and before the 6th cycle (visit 3). Body composition was assessed by bioelectrical impedance analysis (BIA) and confirmed by anthropometric measurements.Thirty patients with NHL were studied. There was no weight change from visit 1-2, but weight increased from visit 2-3 (-1.36 - or + 1.89 kg) and from visit 1-3 (-1.93 + or - 3.21 kg). Patients with weight gain had significantly better overall response rate (p=0.013) and 5-year survival rate (p <0.01). Fat mass increased from visit 1-2 (-1.068 + or - 1.72 kg; p=0.002), from visit 2-3 (-1.32 + or - 1.89 kg; p=0.001) and from visit 1-3 (-2.502 + or - 3.23 kg; p=0.001). There was no statistically significant change in lean body mass (LBM) during chemotherapy. Total body water changed significantly from visit 1-2 (-0.08 + or -2.55l kg; p=0.097), from visit 2-3 (-1.036 + or - 1.10 kg; p=0.001) and from visit 1-3 (-1.89 + or - 3.2l kg; p=0.004). The average relative DI (ARDI) of the R-CHOP regimen was 90% and the rate of complete remission was 63.3%. Overall hematologic toxicity was evident in 14 (46.7%) patients. There was statistical significance between concentrations of cyclophosphamide and doxorubicin (mg/kg fat and mg/kg LBM) whether overall hematologic toxicity was present or not.Patients in the study gained weight during chemotherapy with unfavorable changes in body composition. Attempt has been made to identify clinical variables to predict patients at risk for hematologic toxicity, but an approach for individualizing drug dosing should be continued." @default.
• W21114892 created "2016-06-24" @default.
• W21114892 creator A5058303256 @default.
• W21114892 creator A5063294244 @default.
• W21114892 date "2010-07-27" @default.
• W21114892 modified "2023-09-24" @default.
• W21114892 title "Weight and body composition changes during R-CHOP chemotherapy in patients with non-Hodgkin's lymphoma and their impact on dose intensity and toxicity." @default.
• W21114892 cites W1579001322 @default.
• W21114892 cites W1899541887 @default.
• W21114892 cites W1935045365 @default.
• W21114892 cites W1958341727 @default.
• W21114892 cites W1960111518 @default.
• W21114892 cites W1979243593 @default.
• W21114892 cites W2001536124 @default.
• W21114892 cites W2026901650 @default.
• W21114892 cites W2030387756 @default.
• W21114892 cites W2030544292 @default.
• W21114892 cites W2047427543 @default.
• W21114892 cites W2048792296 @default.
• W21114892 cites W2058340092 @default.
• W21114892 cites W2068008235 @default.
• W21114892 cites W2068673501 @default.
• W21114892 cites W2072187538 @default.
• W21114892 cites W2101713668 @default.
• W21114892 cites W2112163451 @default.
• W21114892 cites W2127206464 @default.
• W21114892 cites W2131136445 @default.
• W21114892 cites W2138012664 @default.
• W21114892 cites W2152474929 @default.
• W21114892 cites W2153335704 @default.
• W21114892 cites W2258896232 @default.
• W21114892 cites W2466623480 @default.
• W21114892 cites W2505250447 @default.
• W21114892 cites W2572374608 @default.
• W21114892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20658724" @default.
• W21114892 hasPublicationYear "2010" @default.
• W21114892 type Work @default.
• W21114892 sameAs 21114892 @default.
• W21114892 citedByCount "7" @default.
• W21114892 countsByYear W211148922012 @default.
• W21114892 countsByYear W211148922015 @default.
• W21114892 countsByYear W211148922016 @default.
• W21114892 countsByYear W211148922017 @default.
• W21114892 crossrefType "journal-article" @default.
• W21114892 hasAuthorship W21114892A5058303256 @default.
• W21114892 hasAuthorship W21114892A5063294244 @default.
• W21114892 hasConcept C120863210 @default.
• W21114892 hasConcept C126322002 @default.
• W21114892 hasConcept C140793950 @default.
• W21114892 hasConcept C147583825 @default.
• W21114892 hasConcept C2776694085 @default.
• W21114892 hasConcept C2779338263 @default.
• W21114892 hasConcept C2779725641 @default.
• W21114892 hasConcept C2780221984 @default.
• W21114892 hasConcept C2781413609 @default.
• W21114892 hasConcept C33872192 @default.
• W21114892 hasConcept C61427482 @default.
• W21114892 hasConcept C71924100 @default.
• W21114892 hasConcept C86803240 @default.
• W21114892 hasConcept C90924648 @default.
• W21114892 hasConceptScore W21114892C120863210 @default.
• W21114892 hasConceptScore W21114892C126322002 @default.
• W21114892 hasConceptScore W21114892C140793950 @default.
• W21114892 hasConceptScore W21114892C147583825 @default.
• W21114892 hasConceptScore W21114892C2776694085 @default.
• W21114892 hasConceptScore W21114892C2779338263 @default.
• W21114892 hasConceptScore W21114892C2779725641 @default.
• W21114892 hasConceptScore W21114892C2780221984 @default.
• W21114892 hasConceptScore W21114892C2781413609 @default.
• W21114892 hasConceptScore W21114892C33872192 @default.
• W21114892 hasConceptScore W21114892C61427482 @default.
• W21114892 hasConceptScore W21114892C71924100 @default.
• W21114892 hasConceptScore W21114892C86803240 @default.
• W21114892 hasConceptScore W21114892C90924648 @default.
• W21114892 hasIssue "2" @default.
• W21114892 hasLocation W211148921 @default.
• W21114892 hasOpenAccess W21114892 @default.
• W21114892 hasPrimaryLocation W211148921 @default.
• W21114892 hasRelatedWork W1972815092 @default.
• W21114892 hasRelatedWork W1998573375 @default.
• W21114892 hasRelatedWork W2011343179 @default.
• W21114892 hasRelatedWork W2060781103 @default.
• W21114892 hasRelatedWork W2101398993 @default.
• W21114892 hasRelatedWork W2107089530 @default.
• W21114892 hasRelatedWork W2127424726 @default.
• W21114892 hasRelatedWork W2368809864 @default.
• W21114892 hasRelatedWork W2527784954 @default.
• W21114892 hasRelatedWork W2529329782 @default.
• W21114892 hasRelatedWork W2573239869 @default.
• W21114892 hasRelatedWork W2579404640 @default.
• W21114892 hasRelatedWork W2739272480 @default.
• W21114892 hasRelatedWork W2885485087 @default.
• W21114892 hasRelatedWork W2902790659 @default.
• W21114892 hasRelatedWork W3031521618 @default.
• W21114892 hasRelatedWork W3031776429 @default.
• W21114892 hasRelatedWork W3169865282 @default.
• W21114892 hasRelatedWork W3181198542 @default.
• W21114892 hasRelatedWork W120970791 @default.

• next