FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111489775> ?p ?o ?g. }

• W2111489775 endingPage "1380" @default.
• W2111489775 startingPage "1367" @default.
• W2111489775 abstract "The chemotactic response of bacteria is mediated by complexes containing two molecules each of a transmembrane receptor and the intracellular signaling proteins CheA and CheW. Mutants in which one or the other of the proteins of this complex are absent, inactive, or expressed at elevated amounts show altered chemotactic behavior and the phenotypes are difficult to interpret for some overexpression mutants. We have examined the possibility that these unexpected phenotypes might arise from the binding steps that lead to active complex formation. A limited genetic algorithm was used to search for sets of binding reactions and associated binding constants expected to give mutant phenotypes in accord with experimental data. Different sets of binding equilibria and different assumptions about the activity of particular receptor complexes were tried. Computer analysis demonstrated that it is possible to obtain sets of binding equilibria consistent with the observed phenotypes and provided a simple explanation for these phenotypes in terms of the distribution of active and inactive complexes formed under various conditions. Optimization methods of this kind offer a unique way to analyze reactions taking place inside living cells based on behavioral data." @default.
• W2111489775 created "2016-06-24" @default.
• W2111489775 creator A5040889565 @default.
• W2111489775 creator A5072860052 @default.
• W2111489775 date "1995-10-01" @default.
• W2111489775 modified "2023-10-16" @default.
• W2111489775 title "Computer analysis of the binding reactions leading to a transmembrane receptor-linked multiprotein complex involved in bacterial chemotaxis." @default.
• W2111489775 cites W1486710313 @default.
• W2111489775 cites W1516216944 @default.
• W2111489775 cites W1529840164 @default.
• W2111489775 cites W1556270322 @default.
• W2111489775 cites W1572250628 @default.
• W2111489775 cites W1577906027 @default.
• W2111489775 cites W1595587942 @default.
• W2111489775 cites W1601572897 @default.
• W2111489775 cites W1754956157 @default.
• W2111489775 cites W1901140685 @default.
• W2111489775 cites W1966944263 @default.
• W2111489775 cites W1976488701 @default.
• W2111489775 cites W1977542956 @default.
• W2111489775 cites W1979035442 @default.
• W2111489775 cites W1979347172 @default.
• W2111489775 cites W1979581724 @default.
• W2111489775 cites W1982186905 @default.
• W2111489775 cites W1986242149 @default.
• W2111489775 cites W1987026072 @default.
• W2111489775 cites W1987930207 @default.
• W2111489775 cites W1997202874 @default.
• W2111489775 cites W2014090222 @default.
• W2111489775 cites W2017139960 @default.
• W2111489775 cites W2029454495 @default.
• W2111489775 cites W2034665579 @default.
• W2111489775 cites W2046578032 @default.
• W2111489775 cites W2048205348 @default.
• W2111489775 cites W2049716406 @default.
• W2111489775 cites W2063902065 @default.
• W2111489775 cites W2064258616 @default.
• W2111489775 cites W2065033398 @default.
• W2111489775 cites W2066307059 @default.
• W2111489775 cites W2069883690 @default.
• W2111489775 cites W2079852902 @default.
• W2111489775 cites W2086438701 @default.
• W2111489775 cites W2089330962 @default.
• W2111489775 cites W2091276334 @default.
• W2111489775 cites W2091848990 @default.
• W2111489775 cites W2092824623 @default.
• W2111489775 cites W2100710904 @default.
• W2111489775 cites W2101755633 @default.
• W2111489775 cites W2103373375 @default.
• W2111489775 cites W2108949591 @default.
• W2111489775 cites W2113394693 @default.
• W2111489775 cites W2115588325 @default.
• W2111489775 cites W2130346159 @default.
• W2111489775 cites W2138160869 @default.
• W2111489775 cites W2141924275 @default.
• W2111489775 cites W2144736357 @default.
• W2111489775 cites W2161554378 @default.
• W2111489775 cites W2165360511 @default.
• W2111489775 cites W2166731355 @default.
• W2111489775 cites W2173955813 @default.
• W2111489775 doi "https://doi.org/10.1091/mbc.6.10.1367" @default.
• W2111489775 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/301293" @default.
• W2111489775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8573792" @default.
• W2111489775 hasPublicationYear "1995" @default.
• W2111489775 type Work @default.
• W2111489775 sameAs 2111489775 @default.
• W2111489775 citedByCount "66" @default.
• W2111489775 countsByYear W21114897752012 @default.
• W2111489775 countsByYear W21114897752013 @default.
• W2111489775 countsByYear W21114897752014 @default.
• W2111489775 countsByYear W21114897752016 @default.
• W2111489775 countsByYear W21114897752020 @default.
• W2111489775 countsByYear W21114897752021 @default.
• W2111489775 crossrefType "journal-article" @default.
• W2111489775 hasAuthorship W2111489775A5040889565 @default.
• W2111489775 hasAuthorship W2111489775A5072860052 @default.
• W2111489775 hasBestOaLocation W21114897752 @default.
• W2111489775 hasConcept C104317684 @default.
• W2111489775 hasConcept C12554922 @default.
• W2111489775 hasConcept C127716648 @default.
• W2111489775 hasConcept C143065580 @default.
• W2111489775 hasConcept C170493617 @default.
• W2111489775 hasConcept C24530287 @default.
• W2111489775 hasConcept C54166955 @default.
• W2111489775 hasConcept C55493867 @default.
• W2111489775 hasConcept C79879829 @default.
• W2111489775 hasConcept C86803240 @default.
• W2111489775 hasConcept C95444343 @default.
• W2111489775 hasConceptScore W2111489775C104317684 @default.
• W2111489775 hasConceptScore W2111489775C12554922 @default.
• W2111489775 hasConceptScore W2111489775C127716648 @default.
• W2111489775 hasConceptScore W2111489775C143065580 @default.
• W2111489775 hasConceptScore W2111489775C170493617 @default.
• W2111489775 hasConceptScore W2111489775C24530287 @default.
• W2111489775 hasConceptScore W2111489775C54166955 @default.
• W2111489775 hasConceptScore W2111489775C55493867 @default.
• W2111489775 hasConceptScore W2111489775C79879829 @default.
• W2111489775 hasConceptScore W2111489775C86803240 @default.

• next