FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111490443> ?p ?o ?g. }

• W2111490443 endingPage "2844" @default.
• W2111490443 startingPage "2836" @default.
• W2111490443 abstract "Adrenocortical carcinoma (ACC) is rare in both adult and pediatric populations. Literature suggests significant differences between children and adults in presentation, histological properties and outcome. The aim of this first nationwide study on pediatric ACC was to describe the incidence, presentation, pathological characteristics, treatment and survival in The Netherlands. All ACC patients aged <20 years at diagnosis and registered in the population-based Netherlands Cancer Registry between 1993 and 2010 were included. Clinical data were extracted from medical records. Archival histological slides were collected via the Dutch Pathology Registry (PALGA). We compared our findings to all clinical studies on pediatric ACC that were found on PubMed. Based on the results, 12 patients were identified: 8 females and 4 males. The median age was 4.1 years (range 1.1-18.6). The population-based age-standardized incidence rate for patients <20 years was 0.18 per million person-years. Autonomous hormonal secretion was present in 10 patients. Seven patients were aged ≤4 years at diagnosis, 5 presented with localized disease and 2 with locally advanced disease. Five patients were aged ≥5 years, 3 presented with distant metastases and 1 with locally advanced disease. For all patients, histological examination displayed malignant characteristics. All patients aged ≤4 years at diagnosis survived; the median follow-up was 97 months (57-179 months). All patients aged ≥5 years died; the median survival was 6 months (0-38 months). Pediatric ACC is extremely rare in the Western world. The clinical outcome was remarkably better in patients aged ≤4 years. This is in accordance with less advanced stage of disease at presentation, yet contrasts with the presence of adverse histological characteristics. Clinical management in advanced disease is adapted from adult practice in the absence of evidence regarding pediatric ACC." @default.
• W2111490443 created "2016-06-24" @default.
• W2111490443 creator A5003532820 @default.
• W2111490443 creator A5031313174 @default.
• W2111490443 creator A5035945818 @default.
• W2111490443 creator A5039590981 @default.
• W2111490443 creator A5043037950 @default.
• W2111490443 creator A5043328708 @default.
• W2111490443 creator A5059720767 @default.
• W2111490443 creator A5075070173 @default.
• W2111490443 creator A5076138289 @default.
• W2111490443 date "2014-09-22" @default.
• W2111490443 modified "2023-10-16" @default.
• W2111490443 title "Adrenocortical carcinoma in children: First population-based clinicopathological study with long-term follow-up" @default.
• W2111490443 cites W1579771167 @default.
• W2111490443 cites W1876202993 @default.
• W2111490443 cites W1909860939 @default.
• W2111490443 cites W1967352082 @default.
• W2111490443 cites W1969237887 @default.
• W2111490443 cites W1969330589 @default.
• W2111490443 cites W1979743377 @default.
• W2111490443 cites W1979932073 @default.
• W2111490443 cites W1981756170 @default.
• W2111490443 cites W1984358699 @default.
• W2111490443 cites W1988995475 @default.
• W2111490443 cites W1998264374 @default.
• W2111490443 cites W1999905872 @default.
• W2111490443 cites W2002793570 @default.
• W2111490443 cites W2010166838 @default.
• W2111490443 cites W2018309178 @default.
• W2111490443 cites W2019210102 @default.
• W2111490443 cites W2023370041 @default.
• W2111490443 cites W2025636912 @default.
• W2111490443 cites W2027355987 @default.
• W2111490443 cites W2027563503 @default.
• W2111490443 cites W2028494477 @default.
• W2111490443 cites W2030696607 @default.
• W2111490443 cites W2032344654 @default.
• W2111490443 cites W2034712686 @default.
• W2111490443 cites W2039836243 @default.
• W2111490443 cites W2041918086 @default.
• W2111490443 cites W2046866551 @default.
• W2111490443 cites W2051484815 @default.
• W2111490443 cites W2054098412 @default.
• W2111490443 cites W2057636125 @default.
• W2111490443 cites W2064487290 @default.
• W2111490443 cites W2066923659 @default.
• W2111490443 cites W2069370693 @default.
• W2111490443 cites W2070089477 @default.
• W2111490443 cites W2070907161 @default.
• W2111490443 cites W2071621793 @default.
• W2111490443 cites W2072921325 @default.
• W2111490443 cites W2073340701 @default.
• W2111490443 cites W2073552456 @default.
• W2111490443 cites W2074606948 @default.
• W2111490443 cites W2076478719 @default.
• W2111490443 cites W2079682166 @default.
• W2111490443 cites W2081203497 @default.
• W2111490443 cites W2082065488 @default.
• W2111490443 cites W2090352142 @default.
• W2111490443 cites W2091955270 @default.
• W2111490443 cites W2093204013 @default.
• W2111490443 cites W2097760515 @default.
• W2111490443 cites W2107297624 @default.
• W2111490443 cites W2120218419 @default.
• W2111490443 cites W2120961400 @default.
• W2111490443 cites W2140359850 @default.
• W2111490443 cites W2141273988 @default.
• W2111490443 cites W2142931016 @default.
• W2111490443 cites W2143697221 @default.
• W2111490443 cites W2161468142 @default.
• W2111490443 cites W2161568796 @default.
• W2111490443 cites W2164015349 @default.
• W2111490443 cites W4245560408 @default.
• W2111490443 doi "https://doi.org/10.3892/or.2014.3506" @default.
• W2111490443 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25241764" @default.
• W2111490443 hasPublicationYear "2014" @default.
• W2111490443 type Work @default.
• W2111490443 sameAs 2111490443 @default.
• W2111490443 citedByCount "34" @default.
• W2111490443 countsByYear W21114904432015 @default.
• W2111490443 countsByYear W21114904432016 @default.
• W2111490443 countsByYear W21114904432017 @default.
• W2111490443 countsByYear W21114904432018 @default.
• W2111490443 countsByYear W21114904432019 @default.
• W2111490443 countsByYear W21114904432020 @default.
• W2111490443 countsByYear W21114904432021 @default.
• W2111490443 countsByYear W21114904432022 @default.
• W2111490443 countsByYear W21114904432023 @default.
• W2111490443 crossrefType "journal-article" @default.
• W2111490443 hasAuthorship W2111490443A5003532820 @default.
• W2111490443 hasAuthorship W2111490443A5031313174 @default.
• W2111490443 hasAuthorship W2111490443A5035945818 @default.
• W2111490443 hasAuthorship W2111490443A5039590981 @default.
• W2111490443 hasAuthorship W2111490443A5043037950 @default.
• W2111490443 hasAuthorship W2111490443A5043328708 @default.
• W2111490443 hasAuthorship W2111490443A5059720767 @default.
• W2111490443 hasAuthorship W2111490443A5075070173 @default.

• next