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- W2111554931 abstract "ABSTRACT The pentraxin SAP reduces neutrophil adhesion to ECM proteins, inhibits the differentiation of monocytes into fibrocytes, attenuates profibrotic macrophages, activates the complement pathway, and promotes phagocytosis of cell debris. Together, these effects of SAP regulate key aspects of inflammation and set a threshold for immune cell activation. Here, we present a review of SAP biology with an emphasis on SAP receptor interactions and how the effect of SAP on monocytes and macrophages has been explored to develop this protein as a therapeutic for renal and lung injuries. We also discuss how there remain many unanswered questions about the role of SAP in innate immunity." @default.
- W2111554931 created "2016-06-24" @default.
- W2111554931 creator A5000020791 @default.
- W2111554931 creator A5028452183 @default.
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- W2111554931 date "2014-05-07" @default.
- W2111554931 modified "2023-10-03" @default.
- W2111554931 title "Serum amyloid P: a systemic regulator of the innate immune response" @default.
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- W2111554931 cites W1624431004 @default.
- W2111554931 cites W1633651668 @default.
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- W2111554931 cites W1797422316 @default.
- W2111554931 cites W1811383523 @default.
- W2111554931 cites W1907417201 @default.
- W2111554931 cites W1966636646 @default.
- W2111554931 cites W1967763945 @default.
- W2111554931 cites W1970823600 @default.
- W2111554931 cites W1974985498 @default.
- W2111554931 cites W1975268714 @default.
- W2111554931 cites W1975809414 @default.
- W2111554931 cites W1977836134 @default.
- W2111554931 cites W1979125021 @default.
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- W2111554931 cites W2009720347 @default.
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- W2111554931 doi "https://doi.org/10.1189/jlb.1mr0114-068r" @default.
- W2111554931 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6607997" @default.
- W2111554931 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24804675" @default.
- W2111554931 hasPublicationYear "2014" @default.
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