Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111566167> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W2111566167 endingPage "62" @default.
- W2111566167 startingPage "55" @default.
- W2111566167 abstract "(RECEIVED FOR PUBLICATIONJULY 17,1950) Themostreliable method forRhesus group determination isprobably thestandard tubemethod(Landsteiner andWiener, 1941; Boorman, Dodd,andMollison, 1942; Taylor, 1943). Thistechnique hasonlyoneserious disadvantage: itmaytakeaslong astwohours toperform, although occasional high-avidity anti-D sera will give clearcutresults in30minutes orevenless. Foremergency Rhesus typing aconsiderably quicker procedure isdesirable. Rapidmethods whichhavebeendescribed include theChowncapillary tubetest (Chown, 1944;ChownandLewis, 1946) andthe Diamondslide test (Diamond andAbelson, 1945). Mollison, Mourant, andRace haverecommended centrifuging after tenminutes' incubation asa meansof accelerating agglutination inthetubemethod. Inpre-transfusion Rhesus grouping inthis laboratory, ithasbeenthepractice forsometimetousetheChownmethod.Theresults werechecked bythetube method carried outbyadifferent observer working inaseparate room.Whereboth tests wereinagreement, itwasassumed thatthecorrect result hadbeenfound: whenever discrepancies occurred, investigations wererepeated until noreasonable doubt remained. After several hundred parallel observations hadbeenmadeinthis way,itbecame clear that theChowntest, atanyratewiththetechnique inuse, was notaltogether satisfactory: bothfalse positive andfalse negative results wereoccasionally encountered. We therefore decided tocarry outanumber ofexperiments to trytodiscover thereasons forincorrect results intheChowntest, andtodetermine asfaraspossible theoptimum conditions forthetest. Atthesametimeatrial ofthe tubecentrifuging methodwasmadeinparallel withtheother twotechniques. Weaiminthis paper tocompare thereliability ofthree methods forRhesus group determination asusedinaroutine laboratory; todrawattention tosomesources of error intheChowntest ;andtodescribe theconditions inwhichsatisfactory results canbeobtained withthetubecentrifuging method. Methods TheChownTest.-A thick suspension ofcells intheir ownserum isobtained byshaking uptheremains ofaclotted specimen ofblood after mostoftheserumhasbeenremoved. This isallowed tofall through acolumn ofanti-D serum inacapillary tubesetupinasmall lumpofplasticine andinclined atanangle of45°.Approximately equal volumes ofcell suspension andanti-D serum areused. Thetest iscarried outatroomtemperature andread after 15minutes. Thistechnique issubstantially thesameasthat advocated byMollison et al. (1948). Standard vaccine capillary tubes havebeenusedinmostoftheexperiments, as" @default.
- W2111566167 created "2016-06-24" @default.
- W2111566167 creator A5009180526 @default.
- W2111566167 creator A5011758092 @default.
- W2111566167 date "1951-02-01" @default.
- W2111566167 modified "2023-09-25" @default.
- W2111566167 title "Emergency Methods for Rhesus Group Determination" @default.
- W2111566167 cites W1964596853 @default.
- W2111566167 cites W2000281339 @default.
- W2111566167 cites W2034984229 @default.
- W2111566167 cites W771500346 @default.
- W2111566167 doi "https://doi.org/10.1136/jcp.4.1.55" @default.
- W2111566167 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1023356" @default.
- W2111566167 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16810907" @default.
- W2111566167 hasPublicationYear "1951" @default.
- W2111566167 type Work @default.
- W2111566167 sameAs 2111566167 @default.
- W2111566167 citedByCount "4" @default.
- W2111566167 crossrefType "journal-article" @default.
- W2111566167 hasAuthorship W2111566167A5009180526 @default.
- W2111566167 hasAuthorship W2111566167A5011758092 @default.
- W2111566167 hasBestOaLocation W21115661671 @default.
- W2111566167 hasConcept C178790620 @default.
- W2111566167 hasConcept C185592680 @default.
- W2111566167 hasConcept C2781311116 @default.
- W2111566167 hasConcept C60644358 @default.
- W2111566167 hasConcept C71924100 @default.
- W2111566167 hasConcept C86803240 @default.
- W2111566167 hasConceptScore W2111566167C178790620 @default.
- W2111566167 hasConceptScore W2111566167C185592680 @default.
- W2111566167 hasConceptScore W2111566167C2781311116 @default.
- W2111566167 hasConceptScore W2111566167C60644358 @default.
- W2111566167 hasConceptScore W2111566167C71924100 @default.
- W2111566167 hasConceptScore W2111566167C86803240 @default.
- W2111566167 hasIssue "1" @default.
- W2111566167 hasLocation W21115661671 @default.
- W2111566167 hasLocation W21115661672 @default.
- W2111566167 hasLocation W21115661673 @default.
- W2111566167 hasLocation W21115661674 @default.
- W2111566167 hasOpenAccess W2111566167 @default.
- W2111566167 hasPrimaryLocation W21115661671 @default.
- W2111566167 hasRelatedWork W1506200166 @default.
- W2111566167 hasRelatedWork W1995515455 @default.
- W2111566167 hasRelatedWork W2048182022 @default.
- W2111566167 hasRelatedWork W2080531066 @default.
- W2111566167 hasRelatedWork W2604872355 @default.
- W2111566167 hasRelatedWork W2748952813 @default.
- W2111566167 hasRelatedWork W2899084033 @default.
- W2111566167 hasRelatedWork W3031052312 @default.
- W2111566167 hasRelatedWork W3032375762 @default.
- W2111566167 hasRelatedWork W3108674512 @default.
- W2111566167 hasVolume "4" @default.
- W2111566167 isParatext "false" @default.
- W2111566167 isRetracted "false" @default.
- W2111566167 magId "2111566167" @default.
- W2111566167 workType "article" @default.