Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111570525> ?p ?o ?g. }
- W2111570525 endingPage "2713" @default.
- W2111570525 startingPage "2702" @default.
- W2111570525 abstract "BacA proteins play key roles in the chronic intracellular infections of Sinorhizobium meliloti , Brucella abortus and Mycobacterium tuberculosis within their respective hosts. S. meliloti , B. abortus and M. tuberculosis BacA-deficient mutants have increased resistance to the thiazole-modified peptide bleomycin. BacA has been previously hypothesized, but not experimentally verified, to be involved in bleomycin uptake. In this paper, we show that a BacA-dependent mechanism is the major route of bleomycin internalization in S. meliloti . We also determined that the B. abortus and S. meliloti BacA proteins are functional homologues and that the B. abortus BacA protein is involved in the uptake of both bleomycin and proline-rich peptides. Our findings also provide evidence that there is a second, BacA-independent minor mechanism for bleomycin internalization in S. meliloti . We determined that the BacA-dependent and -independent mechanisms of bleomycin uptake are energy-dependent, consistent with both mechanisms of bleomycin uptake involving transport systems." @default.
- W2111570525 created "2016-06-24" @default.
- W2111570525 creator A5010832397 @default.
- W2111570525 creator A5014003138 @default.
- W2111570525 creator A5030147398 @default.
- W2111570525 creator A5043081490 @default.
- W2111570525 creator A5059500272 @default.
- W2111570525 creator A5066601506 @default.
- W2111570525 creator A5071069548 @default.
- W2111570525 creator A5076696634 @default.
- W2111570525 creator A5077646079 @default.
- W2111570525 creator A5089417735 @default.
- W2111570525 date "2010-09-01" @default.
- W2111570525 modified "2023-10-01" @default.
- W2111570525 title "Internalization of a thiazole-modified peptide in Sinorhizobium meliloti occurs by BacA-dependent and -independent mechanisms" @default.
- W2111570525 cites W1522262409 @default.
- W2111570525 cites W1530687839 @default.
- W2111570525 cites W1538286201 @default.
- W2111570525 cites W1552540582 @default.
- W2111570525 cites W1631101819 @default.
- W2111570525 cites W1963554693 @default.
- W2111570525 cites W1967745346 @default.
- W2111570525 cites W1969887535 @default.
- W2111570525 cites W1972829752 @default.
- W2111570525 cites W1986818807 @default.
- W2111570525 cites W1991975681 @default.
- W2111570525 cites W1999187539 @default.
- W2111570525 cites W2000254253 @default.
- W2111570525 cites W2007524080 @default.
- W2111570525 cites W2014307101 @default.
- W2111570525 cites W2023807790 @default.
- W2111570525 cites W2035152331 @default.
- W2111570525 cites W2038215655 @default.
- W2111570525 cites W2040954336 @default.
- W2111570525 cites W2046774774 @default.
- W2111570525 cites W2063492068 @default.
- W2111570525 cites W2065194192 @default.
- W2111570525 cites W2068789707 @default.
- W2111570525 cites W2091358620 @default.
- W2111570525 cites W2098590418 @default.
- W2111570525 cites W2111361497 @default.
- W2111570525 cites W2113529168 @default.
- W2111570525 cites W2117734543 @default.
- W2111570525 cites W2119695962 @default.
- W2111570525 cites W2122442673 @default.
- W2111570525 cites W2133094594 @default.
- W2111570525 cites W2133177211 @default.
- W2111570525 cites W2133191145 @default.
- W2111570525 cites W2136207746 @default.
- W2111570525 cites W2142785321 @default.
- W2111570525 cites W2145385227 @default.
- W2111570525 cites W2150042739 @default.
- W2111570525 cites W2151620364 @default.
- W2111570525 cites W2151975768 @default.
- W2111570525 cites W2157614298 @default.
- W2111570525 cites W2165094253 @default.
- W2111570525 cites W4234317413 @default.
- W2111570525 cites W4253090165 @default.
- W2111570525 cites W4300550249 @default.
- W2111570525 cites W885909040 @default.
- W2111570525 cites W98158367 @default.
- W2111570525 doi "https://doi.org/10.1099/mic.0.039909-0" @default.
- W2111570525 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20507886" @default.
- W2111570525 hasPublicationYear "2010" @default.
- W2111570525 type Work @default.
- W2111570525 sameAs 2111570525 @default.
- W2111570525 citedByCount "32" @default.
- W2111570525 countsByYear W21115705252012 @default.
- W2111570525 countsByYear W21115705252013 @default.
- W2111570525 countsByYear W21115705252015 @default.
- W2111570525 countsByYear W21115705252016 @default.
- W2111570525 countsByYear W21115705252017 @default.
- W2111570525 countsByYear W21115705252018 @default.
- W2111570525 countsByYear W21115705252019 @default.
- W2111570525 countsByYear W21115705252020 @default.
- W2111570525 countsByYear W21115705252021 @default.
- W2111570525 countsByYear W21115705252022 @default.
- W2111570525 countsByYear W21115705252023 @default.
- W2111570525 crossrefType "journal-article" @default.
- W2111570525 hasAuthorship W2111570525A5010832397 @default.
- W2111570525 hasAuthorship W2111570525A5014003138 @default.
- W2111570525 hasAuthorship W2111570525A5030147398 @default.
- W2111570525 hasAuthorship W2111570525A5043081490 @default.
- W2111570525 hasAuthorship W2111570525A5059500272 @default.
- W2111570525 hasAuthorship W2111570525A5066601506 @default.
- W2111570525 hasAuthorship W2111570525A5071069548 @default.
- W2111570525 hasAuthorship W2111570525A5076696634 @default.
- W2111570525 hasAuthorship W2111570525A5077646079 @default.
- W2111570525 hasAuthorship W2111570525A5089417735 @default.
- W2111570525 hasConcept C104317684 @default.
- W2111570525 hasConcept C139770010 @default.
- W2111570525 hasConcept C142724271 @default.
- W2111570525 hasConcept C143065580 @default.
- W2111570525 hasConcept C1491633281 @default.
- W2111570525 hasConcept C185592680 @default.
- W2111570525 hasConcept C2776232574 @default.
- W2111570525 hasConcept C2776694085 @default.
- W2111570525 hasConcept C2777304268 @default.