Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111574310> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2111574310 endingPage "122" @default.
- W2111574310 startingPage "118" @default.
- W2111574310 abstract "ffe chemical parameters, antimicrobial activity, and tissue toxicity of two sodium hypochlorite (NaOCl) solutions buffered to a physiologic pH were studied. Initially, a 0.5% NaOCl solution buffered with 3 g of NaH2PO4 per liter was examined. The solution had a pH of 7.49 and an osmolality of 352 mOsmol/liter. When compared with unbuffered and NaHCO3-buffered 0.5% NaOCl solutions, the NaH2PO4-buffered solution was significantly more effective in killing Staphylococcus aureus in vitro. However, the pH of the NaH2PO4-buffered solution decreased over time with a concomitant decrease in antibacterial activity. A freshly prepared solution decontaminated human cadaveric skin colonized by S. aureus, Pseudomonas aeruginosa, or Candida albicans in vitro within 10 min of exposure, whereas a 24-h-old solution cleared the skin of organisms within 15 min. When gauze soaked with 0.5% NaOCl was applied to guinea pig skin for 2 weeks, a 15% decrease in basal cell viabilities was noted. Because of the pH instability and basal cell toxicity, a 0.1% NaOCl solution buffered with NaH2PO4-Na2HPO4 was evaluated. This solution had an osmolality of 386 mOsmol/liter and a pH of 7.4 that was stable over 1 week. A freshly prepared 0.1% NaOCl solution decontaminated skin colonized with S. aureus, C. albicans, and P. aeruginosa within 10, 20, and 30 min, respectively. A 24-h-old solution did not completely decontaminate the colonized skin but significantly reduced the number of microorganisms on the skin surface (P less than 0.001). Application of this solution of guinea pig skin for 2 weeks produced no significant effect on basal cell viabilities. These solutions may serve as alternative topical agents for use in burn therapy." @default.
- W2111574310 created "2016-06-24" @default.
- W2111574310 creator A5014429489 @default.
- W2111574310 creator A5045362239 @default.
- W2111574310 creator A5058933092 @default.
- W2111574310 creator A5082272316 @default.
- W2111574310 date "1985-07-01" @default.
- W2111574310 modified "2023-10-14" @default.
- W2111574310 title "Chemical parameters, antimicrobial activities, and tissue toxicity of 0.1 and 0.5% sodium hypochlorite solutions" @default.
- W2111574310 cites W1535339330 @default.
- W2111574310 cites W1979378086 @default.
- W2111574310 cites W1998909897 @default.
- W2111574310 cites W2009794271 @default.
- W2111574310 cites W2030551959 @default.
- W2111574310 cites W2035575327 @default.
- W2111574310 cites W2049043712 @default.
- W2111574310 cites W2055434888 @default.
- W2111574310 cites W2057103342 @default.
- W2111574310 cites W2065022319 @default.
- W2111574310 cites W2090389496 @default.
- W2111574310 cites W2190330961 @default.
- W2111574310 cites W2247764484 @default.
- W2111574310 cites W2413513256 @default.
- W2111574310 cites W2413591872 @default.
- W2111574310 cites W2417238353 @default.
- W2111574310 cites W55897070 @default.
- W2111574310 cites W2069494279 @default.
- W2111574310 doi "https://doi.org/10.1128/aac.28.1.118" @default.
- W2111574310 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/176321" @default.
- W2111574310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3929674" @default.
- W2111574310 hasPublicationYear "1985" @default.
- W2111574310 type Work @default.
- W2111574310 sameAs 2111574310 @default.
- W2111574310 citedByCount "48" @default.
- W2111574310 countsByYear W21115743102012 @default.
- W2111574310 countsByYear W21115743102013 @default.
- W2111574310 countsByYear W21115743102014 @default.
- W2111574310 countsByYear W21115743102015 @default.
- W2111574310 countsByYear W21115743102016 @default.
- W2111574310 countsByYear W21115743102018 @default.
- W2111574310 countsByYear W21115743102019 @default.
- W2111574310 countsByYear W21115743102020 @default.
- W2111574310 countsByYear W21115743102021 @default.
- W2111574310 countsByYear W21115743102022 @default.
- W2111574310 countsByYear W21115743102023 @default.
- W2111574310 crossrefType "journal-article" @default.
- W2111574310 hasAuthorship W2111574310A5014429489 @default.
- W2111574310 hasAuthorship W2111574310A5045362239 @default.
- W2111574310 hasAuthorship W2111574310A5058933092 @default.
- W2111574310 hasAuthorship W2111574310A5082272316 @default.
- W2111574310 hasBestOaLocation W21115743101 @default.
- W2111574310 hasConcept C178790620 @default.
- W2111574310 hasConcept C185592680 @default.
- W2111574310 hasConcept C2776776456 @default.
- W2111574310 hasConcept C2779489039 @default.
- W2111574310 hasConcept C2780917455 @default.
- W2111574310 hasConcept C29730261 @default.
- W2111574310 hasConcept C43617362 @default.
- W2111574310 hasConcept C4937899 @default.
- W2111574310 hasConcept C523546767 @default.
- W2111574310 hasConcept C537181965 @default.
- W2111574310 hasConcept C54355233 @default.
- W2111574310 hasConcept C86803240 @default.
- W2111574310 hasConcept C89423630 @default.
- W2111574310 hasConceptScore W2111574310C178790620 @default.
- W2111574310 hasConceptScore W2111574310C185592680 @default.
- W2111574310 hasConceptScore W2111574310C2776776456 @default.
- W2111574310 hasConceptScore W2111574310C2779489039 @default.
- W2111574310 hasConceptScore W2111574310C2780917455 @default.
- W2111574310 hasConceptScore W2111574310C29730261 @default.
- W2111574310 hasConceptScore W2111574310C43617362 @default.
- W2111574310 hasConceptScore W2111574310C4937899 @default.
- W2111574310 hasConceptScore W2111574310C523546767 @default.
- W2111574310 hasConceptScore W2111574310C537181965 @default.
- W2111574310 hasConceptScore W2111574310C54355233 @default.
- W2111574310 hasConceptScore W2111574310C86803240 @default.
- W2111574310 hasConceptScore W2111574310C89423630 @default.
- W2111574310 hasIssue "1" @default.
- W2111574310 hasLocation W21115743101 @default.
- W2111574310 hasLocation W21115743102 @default.
- W2111574310 hasLocation W21115743103 @default.
- W2111574310 hasOpenAccess W2111574310 @default.
- W2111574310 hasPrimaryLocation W21115743101 @default.
- W2111574310 hasRelatedWork W1603882315 @default.
- W2111574310 hasRelatedWork W196667843 @default.
- W2111574310 hasRelatedWork W2056756819 @default.
- W2111574310 hasRelatedWork W2351223138 @default.
- W2111574310 hasRelatedWork W2358416950 @default.
- W2111574310 hasRelatedWork W2398140429 @default.
- W2111574310 hasRelatedWork W2890410687 @default.
- W2111574310 hasRelatedWork W2890576590 @default.
- W2111574310 hasRelatedWork W2912210505 @default.
- W2111574310 hasRelatedWork W63521441 @default.
- W2111574310 hasVolume "28" @default.
- W2111574310 isParatext "false" @default.
- W2111574310 isRetracted "false" @default.
- W2111574310 magId "2111574310" @default.
- W2111574310 workType "article" @default.