FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111607293> ?p ?o ?g. }

• W2111607293 endingPage "554" @default.
• W2111607293 startingPage "543" @default.
• W2111607293 abstract "The atomic models of the ribosomal subunits, togetherwith structural investigations of functional ribosomalcomplexes by X-ray crystallography and 3D cryo-EM,have led to a basic understanding of the structure and dynamics of protein biosynthesis in prokaryotic systems. Incontrast, our knowledge about eukaryotic ribosomes issparse. The evolutionary conservation of rRNA and ribosomal proteins suggests that the ribosomal subunits sharea similar spatial arrangement and that the fundamentalmechanism of protein biosynthesis is the same. However,the actual degree of similarity is not known, and significant differences are known to exist. Due to insertion elements in the rRNA molecules (Gerbi 1996) and the presence of 20 to 30 additional proteins (Wittmann-Liebold1986; Wool et al. 1990; Planta and Mager 1998), eukaryotic ribosomes are larger than their prokaryotic counterparts. There are functional differences, e.g., in the mechanism of initiation (Sachs et al. 1997), or in themechanism of elongation, as demonstrated by EF3, athird elongation factor in yeast (Triana-Alonso et al.1995). Additionally, several antibiotics are specific forone class of ribosomes or the other (Spahn and Prescott1996). Furthermore, the ribosome has to play a role inother biological processes in the cell such as protein folding (Hardesty et al. 2000) and protein transport (Beckmann et al. 1997, 2001; Menetret et al. 2000). Bindingand recognition events in these processes do not necessarily take place at those ribosomal sites that are highlyconserved among bacterial and eukaryotic ribosomes.These and other differences in function are likely to bereflected by differences in structure..." @default.
• W2111607293 created "2016-06-24" @default.
• W2111607293 creator A5010441616 @default.
• W2111607293 creator A5042033531 @default.
• W2111607293 creator A5042892654 @default.
• W2111607293 creator A5081060821 @default.
• W2111607293 date "2001-01-01" @default.
• W2111607293 modified "2023-09-25" @default.
• W2111607293 title "The Active 80S Ribosome-Sec61 Complex" @default.
• W2111607293 cites W1193160299 @default.
• W2111607293 cites W1677689941 @default.
• W2111607293 cites W1965170134 @default.
• W2111607293 cites W1968451768 @default.
• W2111607293 cites W1969855294 @default.
• W2111607293 cites W1980355157 @default.
• W2111607293 cites W1983534198 @default.
• W2111607293 cites W1985532457 @default.
• W2111607293 cites W1988085802 @default.
• W2111607293 cites W1994742864 @default.
• W2111607293 cites W1994918408 @default.
• W2111607293 cites W2001949118 @default.
• W2111607293 cites W2006132807 @default.
• W2111607293 cites W2006135655 @default.
• W2111607293 cites W2018530089 @default.
• W2111607293 cites W2020721543 @default.
• W2111607293 cites W2022572800 @default.
• W2111607293 cites W2025170604 @default.
• W2111607293 cites W2026542719 @default.
• W2111607293 cites W2029314164 @default.
• W2111607293 cites W2045690036 @default.
• W2111607293 cites W2049130730 @default.
• W2111607293 cites W2049701913 @default.
• W2111607293 cites W2051164564 @default.
• W2111607293 cites W2061146689 @default.
• W2111607293 cites W2062887711 @default.
• W2111607293 cites W2065820275 @default.
• W2111607293 cites W2071748696 @default.
• W2111607293 cites W2075448557 @default.
• W2111607293 cites W2077634814 @default.
• W2111607293 cites W2082270046 @default.
• W2111607293 cites W2088264371 @default.
• W2111607293 cites W2093471887 @default.
• W2111607293 cites W2096190827 @default.
• W2111607293 cites W2097654784 @default.
• W2111607293 cites W2100654918 @default.
• W2111607293 cites W2103356759 @default.
• W2111607293 cites W2108551329 @default.
• W2111607293 cites W2113942795 @default.
• W2111607293 cites W2117761303 @default.
• W2111607293 cites W2118016880 @default.
• W2111607293 cites W2119966574 @default.
• W2111607293 cites W2128897252 @default.
• W2111607293 cites W2129096064 @default.
• W2111607293 cites W2149963584 @default.
• W2111607293 cites W2152698588 @default.
• W2111607293 cites W2154183572 @default.
• W2111607293 cites W2157729659 @default.
• W2111607293 cites W2164282000 @default.
• W2111607293 cites W2165165230 @default.
• W2111607293 cites W2169597956 @default.
• W2111607293 cites W2169863303 @default.
• W2111607293 cites W2170243611 @default.
• W2111607293 cites W2240090228 @default.
• W2111607293 cites W3206599079 @default.
• W2111607293 cites W4230988890 @default.
• W2111607293 cites W4237255351 @default.
• W2111607293 cites W4241563925 @default.
• W2111607293 cites W4376849510 @default.
• W2111607293 cites W890226141 @default.
• W2111607293 doi "https://doi.org/10.1101/sqb.2001.66.543" @default.
• W2111607293 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12762056" @default.
• W2111607293 hasPublicationYear "2001" @default.
• W2111607293 type Work @default.
• W2111607293 sameAs 2111607293 @default.
• W2111607293 citedByCount "9" @default.
• W2111607293 countsByYear W21116072932014 @default.
• W2111607293 countsByYear W21116072932018 @default.
• W2111607293 countsByYear W21116072932022 @default.
• W2111607293 crossrefType "journal-article" @default.
• W2111607293 hasAuthorship W2111607293A5010441616 @default.
• W2111607293 hasAuthorship W2111607293A5042033531 @default.
• W2111607293 hasAuthorship W2111607293A5042892654 @default.
• W2111607293 hasAuthorship W2111607293A5081060821 @default.
• W2111607293 hasConcept C104317684 @default.
• W2111607293 hasConcept C112755997 @default.
• W2111607293 hasConcept C129194359 @default.
• W2111607293 hasConcept C139124968 @default.
• W2111607293 hasConcept C301363 @default.
• W2111607293 hasConcept C3675279 @default.
• W2111607293 hasConcept C38062823 @default.
• W2111607293 hasConcept C55493867 @default.
• W2111607293 hasConcept C67705224 @default.
• W2111607293 hasConcept C67905577 @default.
• W2111607293 hasConcept C70721500 @default.
• W2111607293 hasConcept C86803240 @default.
• W2111607293 hasConcept C88478588 @default.
• W2111607293 hasConcept C95444343 @default.
• W2111607293 hasConceptScore W2111607293C104317684 @default.

• next