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- W2111664118 abstract "The effect of diethylcarbamazine (DEC)treatment on the concentrationof histamine(H)and someother biogenicaminesnamelydopamine(DA),norepinephrine (NE), epinephrine(E) and 5-hydroxytryptamine(5-HT) has been investigatedin differentbrain regionsand someperipheraltissues of normaland Acanthocheilonema viteaeinfectedadult Mastomys natalensis.DuringAcanthocheilonema viteaeinfectionhistaminelevel increased significantly in cerebral hemispheres, mid-brain hypothalamus,lungs. The levels of monoamineswere unaffected. Histaminelevel significantlyincreased in all the organs studied, except adrenal glands, three hours after diethylcarbamazine (DEC)treatment on normalas wellas filaria-infected mastomys.Enhancement in histaminelevelof tissuesafter DEC treatment was not responsible for developmentof allergic reactions in infected animals.Neverthelesschangesin hypothalamic histamineconcentration may be involvedin the genesisof DECinducedfever." @default.
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- W2111664118 date "1991-06-29" @default.
- W2111664118 modified "2023-09-25" @default.
- W2111664118 title "Acanthocheilonema viteae in Mastomys natalensis : Contents of Certain Biogenic Amines in Brain and Other Peripheral Tissues following Diethylcarbamazine Treatment." @default.
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