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• W2111666911 abstract "Malignant transformation of vestibular schwannoma is considered a rare clinical entity. Radiotherapy, as a treatment option for vestibular schwannoma, is regarded as a potential risk factor for secondary malignancy. Recently, radiotherapy with dose fractionation has been proposed, intended to diminish the risk of radiation-induced neuropathy. The aim of the present study is to report the first case, to the best of our knowledge, of malignant transformation of a residual vestibular schwannoma 19 years after fractionated radiotherapy, describing its characteristics with regard to those previously reported in the literature. The main purpose of the present work is to state that the knowledge of the iatrogenic potential pitfalls of any technique of radiotherapy in clinical oncology is becoming a necessity. Finally, our report demonstrates that the irradiated patients must be monitored for life because a secondary malignancy may appear after a very long delay." @default.
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• W2111666911 date "2012-01-01" @default.
• W2111666911 modified "2023-10-01" @default.
• W2111666911 title "Unique case of malignant transformation of a vestibular schwannoma after fractionated radiotherapy" @default.
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• W2111666911 doi "https://doi.org/10.1016/j.amjoto.2011.02.006" @default.
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