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- W2111736142 abstract "Water-soluble low molecular weight chitosan of nanometer level and its copper complexes were prepared, and characterized by IR spectra, elemental analysis and gel permeation chromatography (GPC). The modes and mechanism of these copper complexes interaction with DNA were studied by a fluorescent probe method and electrophoresis analysis. It is suggested that there are electrostatic and intercalation modes of copper complexes interacting with DNA. At first, the cationic complex electrostaticly binds to the negatively charged phosphate backbone of DNA, and then a portion of the complex intercalates between the base pairs on the DNA duplex strand. Copyright © 2005 John Wiley & Sons, Ltd." @default.
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- W2111736142 date "2005-01-01" @default.
- W2111736142 modified "2023-10-18" @default.
- W2111736142 title "The preparation of nano-scope chitosan-oligomer copper complexes and their interaction with DNA" @default.
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- W2111736142 doi "https://doi.org/10.1002/pat.627" @default.
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